Ievins, Alexander D., Moughton, Adam O. and O’Reilly, Rachel K.. (2008) Synthesis of hollow responsive functional nanocages using a metal–ligand complexation strategy. Macromolecules, Vol.41 (No.10). pp. 3571-3578. ISSN 0024-9297

Full text not available from this repository.

Abstract

A metal–ligand complexation strategy using ruthenium−terpyridine interactions was utilized for the facile synthesis of amphiphilic block copolymers which were self-assembled into spherical micelles and stabilized throughout their shell to afford well-defined nanoparticles. The labile metal–ligand bond at the nanoparticle core–shell interface was then readily broken to enable excavation to afford hollow completely hydrophilic nanocages which can no longer sequester hydrophobic small molecules. These nanocages also demonstrated pH responsiveness and could be further functionalized by the reintroduction of metals.

[error in script] [error in script]

Item Type:	Journal Article
Subjects:	Q Science > QD Chemistry T Technology > TA Engineering (General). Civil engineering (General)
Divisions:	Faculty of Science > Chemistry
Library of Congress Subject Headings (LCSH):	Nanostructured materials -- Synthesis, Block copolymers, Self-assembly (Chemistry), Micelles, Nanoparticles, Transition metal complexes, Ligands
Journal or Publication Title:	Macromolecules
Publisher:	American Chemical Society
ISSN:	0024-9297
Date:	2008
Volume:	Vol.41
Number:	No.10
Page Range:	pp. 3571-3578
Identification Number:	10.1021/ma800047r
Status:	Peer Reviewed
Publication Status:	Published
Funder:	Engineering and Physical Sciences Research Council (EPSRC), Interdisciplinary Research Collaboration in Nanotechnology, Royal Society (Great Britain), Downing College (University of Cambridge), Nuffield Foundation
References:	(1) Zhang, L. F.; Yu, K.; Eisenberg, A. Science 1996, 272, 1777–1779. (2) Zhang, L. F.; Eisenberg, A. J. Am. Chem. Soc. 1996, 118, 3168– 3181. (3) Webber, S. E. J. Phys. Chem. B 1998, 102, 2618–2626. (4) Discher, D. E.; Eisenberg, A. Science 2002, 297, 967–973. (5) Matejicek, P.; et al. Macromolecules 2002, 35, 9487–9496. (6) Chen, Z.; et al. J. Am. Chem. Soc. 2005, 127, 8592–8593. (7) Butun, V.; Lowe, A. B.; Billingham, N. C.; Armes, S. P. J. Am. Chem. Soc. 1999, 121, 4288–4289. (8) Wooley, K. L. J. Polym. Sci., Part A: Polym. Chem. 2000, 38, 1397– 1407. (9) Lodge, T. P. Macromol. Chem. Phys. 2003, 204, 265–273. (10) Ma, Q.; Remsen, E. E.; Kowalewski, T.; Wooley, K. L. J. Am. Chem. Soc. 2001, 123, 4627–4628. (11) Ding, J. F.; Liu, G. J. Macromolecules 1998, 31, 6554–6558. (12) Wooley, K. L. Chem.-Eur. J. 1997, 3, 1397–1399. (13) Thurmond, K. B.; Kowalewski, T.; Wooley, K. L. J. Am. Chem. Soc. 1996, 118, 7239–7240. (14) Thurmond, K. B.; Kowalewski, T.; Wooley, K. L. J. Am. Chem. Soc. 1997, 119, 6656–6665. (15) Cao, L.; Manners, I.; Winnik, M. A. Macromolecules 2001, 34, 3353– 3360. (16) Won, Y.-Y.; Paso, K.; Davis, H. T.; Bates, F. S. J. Phys. Chem. B 2001, 105, 8302–8311. (17) Massey, J.; Power, K. N.; Manners, I.; Winnik, M. A. J. Am. Chem. Soc. 1998, 120, 9533–9540. (18) Kim, Y.; Dalhaimer, P.; Christian, D. A.; Discher, D. E. Nanotechnology 2005, 16, S484–S491. (19) Li, Y.; Liu, G. Langmuir 2003, 19, 10480–10486. (20) Yoshida, T.; Taribagil, R.; Hillmyer, M. A.; Lodge, T. P. Macromolecules 2007, 40, 1615–1623. (21) Choucair, A.; Lavigueur, C.; Eisenberg, A. Langmuir 2004, 20, 3894– 3900. (22) Terreau, O.; Luo, L. B.; Eisenberg, A. Langmuir 2003, 19, 5601– 5607. (23) Discher, B. M.; et al. Science 1999, 284, 1143–1146. (24) Zhang, L. F.; Eisenberg, A. Science 1995, 268, 1728–1731. (25) Nardin, C.; Hirt, T.; Leukel, J.; Meier, W. Langmuir 2000, 16, 1035– 1041. (26) O’Reilly, R. K.; Hawker, C. J.; Wooley, K. L. Chem. Soc. ReV 2006, 35, 1068–1083. (27) Read, E. S.; Armes, S. P. Chem. Commun. 2007, 3021–3035. (28) Huang, H. Y.; Remsen, E. E.; Kowalewski, T.; Wooley, K. L. J. Am. Chem. Soc. 1999, 121, 3805–3806. (29) Cheng, C.; Qi, K.; Khoshdel, E.; Wooley, K. L. J. Am. Chem. Soc. 2006, 6808–6809. (30) Ma, Q.; et al. Nano. Lett. 2001, 1, 651–655. (31) Murthy, K. S.; et al. Chem. Commun. 2001, 773–774. (32) Turner, J. L.; Chen, Z.; Wooley, K. L. J. Controlled Release 2005, 109, 189–202. (33) Katagiri, K.; Matsuda, A.; Caruso, F. Macromolecules 2006, 39, 8067–8074. (34) Jang, J.; Lee, K. Chem. Commun. 2002, 1098–1099. (35) Wang, J.; Jiang, M. J. Am. Chem. Soc. 2006, 128, 3703–3708. (36) Zhang, Y.; et al. AdV. Funct. Mater. 2005, 15, 695–699. (37) Donath, E.; et al. Angew. Chem., Int. Ed. 1998, 37, 2201–2205. (38) Wendland, M.; Zimmerman, S. C. J. Am. Chem. Soc. 1999, 121, 1389–1390. (39) Kim, D.; et al. Angew. Chem., Int. Ed. 2007, 46, 3471–3474. (40) Sauer, M.; Meier, W. Chem. Commun. 2001, 55–56. (41) Han, J.; Song, G.; Guo, R. AdV. Mater. 2006, 18, 3140–3144. (42) Sanji, T.; Nakatsuka, Y.; Ohnishi, S.; Sakurai, H. Macromolecules 2000, 33, 8524–8526. (43) Meier, W. Chem. Soc. ReV. 2000, 29, 295–303. (44) Hamley, I. M. Soft Matter 2005, 1, 36–43. (45) Chen, D. Y.; Jiang, M. Acc. Chem. Res. 2005, 38, 494–502. (46) Peyratout, C. S.; Dahne, L. Angew. Chem., Int. Ed. 2004, 43, 3762– 3783. (47) Brunseld, L.; Folmer, B. J. B.; Sijbesma, R. P.; Meijer, E. W. Chem. ReV. 2001, 101, 4071–4097. (48) Elemans, J. A. A. W.; Rowan, A. E.; Nolte, R. J. M. J. Mater. Chem. 2003, 13, 2661–2670. (49) South, C. R.; Budd, C.; Weck, M. Acc. Chem. Res. 2007, 40, 63–74. (50) Zhang, Y.; Xiang, M.; Jiang, M.; Wu, C. Macromolecules 1997, 30, 6084–6089. (51) Kawakami, T.; Kato, T. Macromolecules 1998, 31, 4475–4479. (52) Wang, M.; et al. Macromolecules 2001, 34, 7172–7178. (53) Yuan, X. F.; et al. Langmuir 2001, 17, 6122–6126. (54) Ciferri, A. Macromol. Rapid Commun. 2002, 23, 511–529. (55) Zhang, Y.; et al. Macromolecules 2004, 37, 1537–1543. (56) Duan, H.; et al. J. Am. Chem. Soc. 2001, 123, 12097–098. (57) Wang, M.; et al. Macromolecules 2002, 35, 5980–5989. (58) Lohmeijer, B. G. G.; Schubert, U. S. J. Polym. Sci., Part A: Polym. Chem. 2003, 41, 1413–1427. (59) Hofmeier, H.; Schubert, U. S. Chem. Soc. ReV. 2004, 33, 373–399. (60) Andres, P. R.; Schubert, U. S. AdV. Mater. 2004, 16, 1043–1068. (61) Fraser, C. L.; Smith, A. P.; Wu, X. J. Am. Chem. Soc. 2000, 122, 9026–9027. (62) Lamba, J. J. S.; Fraser, C. L. J. Am. Chem. Soc. 1997, 119, 1801– 1802. (63) Beck, J. B.; Ineman, J. M.; Rowan, S. J. Macromolecules 2005, 38, 5060–5068. (64) Pollino, J. M.; Weck, M. Chem. Soc. ReV. 2005, 34, 193–207. (65) Hofmeier, H.; et al. Aust. J. Chem. 2004, 57, 419–426. (66) Smith, A. P.; Fraser, C. L. Macromolecules 2003, 36, 2654–2660. (67) Gohy, J. F.; Lohmeijer, B. G. G.; Schubert, U. S. Macromol. Rapid Commun. 2002, 23, 555–560. (68) Gohy, J. F.; et al. Macromolecules 2002, 35, 9748–9755. (69) Gohy, J. F.; Lohmeijer, B. G. G.; Varshney, S. K.; Schubert, U. S. Macromolecules 2002, 35, 7427–7435. (70) Gohy, J. F.; Hofmeier, H.; Alexeev, A.; Schubert, U. S. Macromol. Chem. Phys. 2003, 204, 1524–1530. (71) Gohy, J. F.; Lohmeijer, B. G. G.; Schubert, U. S. Macromolecules 2002, 35, 4560–4563. (72) Guillet, P.; et al. Macromolecules 2006, 39, 5484–5488. (73) Benoit, D.; Chaplinski, V.; Braslau, R.; Hawker, C. J. J. Am. Chem. Soc. 1999, 121, 3904–3920. (74) Schubert, U. S.; Schmatloch, S.; Precup, A. A. Des. Monom. Polym. 2002, 5, 211–221. (75) Lohmeijer, B. G. G.; Schubert, U. S. J. Polym. Sci., Part A: Polym. Chem. 2004, 42, 4016–4027. (76) Evans, D. F. J. Chem. Soc. 1959, 2003–2006. (77) Hoogenboom, R.; Schubert, U. S. Chem. Soc. ReV. 2006, 35, 622– 629. (78) Smith, A. P.; Fraser, C. L. Macromolecules 2002, 35, 594–596. (79) Smith, A. P.; Fraser, C. L. Macromolecules 2003, 36, 5520–5525. (80) Lohmeijer, B. G. G.; Schubert, U. S. Macromol. Chem. Phys. 2003, 204, 1072–1078. (81) Lohmeijer, B. G. G.; Schlaad, H.; Schubert, U. S. Macromol. Symp. 2003, 196, 125–135. (82) Lohmeijer, B. G. G.; Schubert, U. S. Angew. Chem., Int. Ed. 2002, 41, 3825–3829. (83) Hawker, C. J.; Bosman, A. W.; Harth, E. Chem. ReV. 2001, 101, 3661–3688. (84) Matyjaszewski, K.; Xia, J. H. Chem. ReV. 2001, 101, 2921–2990. (85) Kamigaito, M.; Ando, T.; Sawamoto, M. Chem. ReV. 2001, 101, 3689–3745. (86) Chiefari, J.; et al. Macromolecules 1998, 31, 5559–5562. (87) Georges, M. K.; Veregin, R. P. N.; Kazmaier, P. M.; Hamer, G. K. Macromolecules 1993, 26, 2987–2988. (88) Mayadunne, R. T. A.; et al. Macromolecules 1999, 32, 6977–6980. (89) Zhang, L.; Zhang, Y.; Chen, Y. Eur. Polym. J. 2006, 42, 2398–2406. (90) Zhou, G.; Harruna, I. I. Macromolecules 2005, 38, 4114–4123. (91) Meier, M. A. R.; Lohmeijer, B. G. G.; Schubert, U. S. Macromol. Rapid Commun. 2003, 24, 852–857. (92) Schubert, U. S.; Hofmeier, H. Macromol. Rapid Commun. 2002, 23, 561–566. (93) Heller, M.; Schubert, U. S. Macromol. Rapid Commun. 2002, 23, 411–415. (94) Ma, Q.; Wooley, K. L. J. Polym. Sci., Part A: Polym. Chem. 2000, 38, 4805–4820. (95) Hofmeier, H.; Schubert, U. S. Macromol. Chem. Phys. 2003, 204, 1391–1397. (96) Chiper, M.; Meier, M. A. R.; Kranenburg, J. M.; Schubert, U. S. Macromol. Chem. Phys. 2007, 208, 679–689. (97) Turner, J. L.; Wooley, K. L. Nano Lett. 2004, 4, 683–688. (98) Dou, H.; et al. Angew. Chem., Int. Ed. 2003, 42, 1516–1519. (99) Rodriguez-Hernandez, J.; Lecommandoux, S. J. Am. Chem. Soc. 2005, 127, 2026–2027. (100) Du, J.; Tang, Y.; Lewis, A. L.; Armes, S. P. J. Am. Chem. Soc. 2005, 127, 17982–17983. (101) Morishima, Y. Angew. Chem., Int. Ed. 2007, 46, 1370–1372. (102) Liepold, L. O.; et al. Phys. Biol. 2005, 2, S166–S172.
URI:	http://wrap.warwick.ac.uk/id/eprint/40571

Request changes to a record

Actions (login required)

View Item