Gunawardana, Lihini, Zammit, Stanley, Lewis, Glyn, Gunnell, David, Hollis, Chris, Wolke, Dieter and Harrison, Glynn. (2011) Examining the association between maternal analgesic use during pregnancy and risk of psychotic symptoms during adolescence. Schizophrenia Research, Vol.126 (No.1-3). pp. 220-225. ISSN 0920-9964

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Abstract

Medications such as aspirin that interfere with the prostaglandin pathway, taken during pregnancy, may influence the risk of schizophrenia in the offspring. Other epidemiological studies are needed to examine this association further.

Item Type:	Journal Article
Subjects:	B Philosophy. Psychology. Religion > BF Psychology R Medicine > RG Gynecology and obstetrics R Medicine > RJ Pediatrics
Divisions:	Faculty of Medicine > Warwick Medical School > Mental Health and Wellbeing Faculty of Science > Psychology
Library of Congress Subject Headings (LCSH):	Psychoses in adolescence, Pregnant women -- Drug use, Analgesics, Fetus -- Effect of drugs on, Obstetrical pharmacology
Journal or Publication Title:	Schizophrenia Research
Publisher:	Elsevier BV
ISSN:	0920-9964
Date:	2011
Volume:	Vol.126
Number:	No.1-3
Page Range:	pp. 220-225
Identification Number:	10.1016/j.schres.2010.10.021
Status:	Peer Reviewed
Publication Status:	Published
Funder:	Wellcome Trust (London, England), Wales. National Assembly
Grant number:	GR072043MA (WT)
References:	Barr, C.E., Mednick, S.A., Munk-Jorgensen, P., 1990. Exposure to influenza epidemics during gestation and adult schizophrenia. A 40-year study. Arch. Gen. Psychiatry 47, 869–874. Berger, G.E.,Wood, S.J., Pantelis, C., Velakoulis, D.,Wellard, R.M.,McGorry, P.D., 2002. Implications of lipid biology for the pathogenesis of schizophrenia. Aust N Z J Psychiatry 36, 355–366. Boksa, P., 2008. Maternal infection during pregnancy and schizophrenia. J. Psychiatry Neurosci. 33, 183–185. Brown, A.S., Cohen, P., Greenwald, S., Susser, E., 2000. Nonaffective psychosis after prenatal exposure to rubella. Am. J. Psychiatry 157, 438–443. Brown, A.S., Susser, E.S., 2008. Prenatal nutritional deficiency and risk of adult schizophrenia. Schizophr. Bull. 34, 1054–1063. Buretic-Tomljanovic, A., Giacometti, J., Nadalin, S., Rubesa, G., Vulin, M., Tomljanovic, D., 2008. Phospholipid membrane abnormalities and reduced niacin skin flush response in schizophrenia. Psychiatr. Danub. 20, 372–383. Byrne, M., Agerbo, E., Bennedsen, B., Eaton, W.W., Mortensen, P.B., 2007. Obstetric conditions and risk of first admission with schizophrenia: a Danish national register based study. Schizophr. Res. 97, 51–59. Cannon, M., Jones, P.B., Murray, R.M., 2002. Obstetric complications and schizophrenia: historical and meta-analytic review. Am. J. Psychiatry 159, 1080–1092. Edwards, M.J., 2007. Hyperthermia in utero due to maternal influenza is an environmental risk factor for schizophrenia. CongenitAnomKyoto 47, 84–89. Dalman, C., Allebeck, P., Gunnell, D., Harrison, G., Kristensson, K., Lewis, G., Lofving, S., Rasmussen, F.,Wicks, S., Karlsson, H., 2008. Infections in the CNS during childhood and the risk of subsequent psychotic illness: a cohort study of more than one million Swedish subjects. Am. J. Psychiatry 165, 59–65. Fatemi, S.H., Folsom, T.D., 2009. The neurodevelopmental hypothesis of schizophrenia, revisited. Schizophr. Bull. 35, 528–548. Fruntes, V., Limosin, F., 2008. Schizophrenia and viral infection during neurodevelopment: a pathogenesis model? Med. Sci.Monit. 14, RA71–RA77. Golding, J., Pembrey, M., Jones, R., 2001. ALSPAC—the Avon Longitudinal Study of Parents and Children. I. Study methodology. Paediatr. Perinat. Epidemiol. 15, 74–87. Hillbrand, M., Spitz,R.T., VandenBos, G.R., 1997. Investigating the role of lipids in mood, aggression, and schizophrenia. Psychiatr. Serv. 48 (875–876), 882. Horwood, J., Thomas, K., Duffy, L., Gunnell, D., Hollis, C., Lewis, G., Thompson, A., Wolke, D., Zammit, S., Harrison, G., 2008. Frequency of psychosis-like symptoms in a non-clinical population of 12 year olds: results from the ALSPAC birth cohort. Schizophr. Res. 98, 77–78. Kelleher, I., Harley,M., Lynch, F., Arseneault, L., Fitzpatrick, C., Cannon,M., 2008. Associations between childhood trauma, bullying and psychotic symptoms among a school-based adolescent sample. Br. J. Psychiatry 193, 378–382. Leonhardt, 2003. Low-dose aspirin in pregnancy:maternal and neonatal aspirin concentrations and neonatal prostanoid formation. Pediatrics 3, e77–e81. Limosin, F., Rouillon, F., Payan, C., Cohen, J.-M., 2003. Prenatal exposure to influenza as a risk factor for adult schizophrenia. Acta Psychiatr. Scand. 107, 331–335. Mortensen, P.B., Pedersen, M.G., Pedersen, C.B., 2010. Psychiatric family history and schizophrenia risk in Denmark: which mental disorders are relevant? Psychol. Med. 40, 201–210. Poulton, R., Caspi, A., Moffitt, T.E., Cannon, M., Murray, R., Harrington, H., 2000. Children's self-reported psychotic symptoms and adult schizophreniform disorder: a 15-year longitudinal study. Arch. Gen. Psychiatry 57, 1053–1058. Reddy, R.D., Yao, J.K., 2003. Environmental factors and membrane polyunsaturated fatty acids in schizophrenia. Prostaglandins Leukot. Essent. Fatty Acids 69, 385–391. Shaffer, D., Fisher, P., Lucas, C.P., Dulcan,M.K., Schwab-Stone,M.E., 2000. NIMH Diagnostic Interview Schedule for Children Version IV (NIMH DISC-IV): description, differences from previous versions, and reliability of some common diagnoses. J. Am. Acad. Child Adolesc. Psychiatry 39, 28–38. Skosnik, P.D., Yao, J.K., 2003. From membrane phospholipid defects to altered neurotransmission: is arachidonic acid a nexus in the pathophysiology of schizophrenia? Prostaglandins Leukot. Essent. Fatty Acids 69, 367–384. Sorensen, H.J., Mortensen, E.L., Reinisch, J.M., Mednick, S.A., 2004. Association between prenatal exposure to analgesics and risk of schizophrenia. Br. J. Psychiatry 185, 366–371. Sorensen, H.J., Mortensen, E.L., Reinisch, J.M., Mednick, S.A., 2009. Association between prenatal exposure to bacterial infection and risk of schizophrenia. Schizophr. Bull. 35, 631–637. Spauwen, J., Krabbendam, L., Lieb, R., Wittchen, H.U., & van Os, J., 2004. Early maternal stress and health behaviours and offspring expression of psychosis in adolescence. Acta. Psychiatr. Scand. 110, 356–364. van Os, J., Linscott, R.J., Myin-Germeys, I., Delespaul, P., Krabbendam, L., 2009. A systematic review and meta-analysis of the psychosis continuum: evidence for a psychosis proneness-persistence-impairment model of psychotic disorder. Psychol. Med. 39, 179–195. WHO, 1994. Schedules for Clinical Assessment in Neuropsychiatry. American Psychiatric Research, Washington, DC. Wicks, S., Hjern, A., Gunnell, D., Lewis, G., Dalman, C., 2005. Social adversity in childhood and the risk of developing psychosis: a national cohort study. Am. J. Psychiatry 162, 1652–1657. Zammit, S., Allebeck, P., Dalman, C., Lundberg, I., Hemmingson, T., Owen, M.J., Lewis, G., 2003. Paternal age and risk for schizophrenia. Br. J. Psychiatry 183, 405–408. Zammit, S., Odd, D., Horwood, J., Thompson, A., Thomas, K., Menezes, P., Gunnell, D., Hollis, C., Wolke, D., Lewis, G., Harrison, G., 2009a. Investigating whether adverse prenatal and perinatal events are associated with non-clinical psychotic symptoms at age 12 years in the ALSPAC birth cohort. Psychol. Med. 39, 1457–1467. Zammit, S., Thomas, K., Thompson, A., Horwood, J., Menezes, P., Gunnell, D., Hollis, C., Wolke, D., Lewis, G., Harrison, G., 2009b. Maternal tobacco, cannabis and alcohol use during pregnancy and risk of adolescent psychotic symptoms in offspring. Br. J. Psychiatry 195, 294–300.
URI:	http://wrap.warwick.ac.uk/id/eprint/40824

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