The Library
Association of regional gray matter volume loss and progression of white matter lesions in multiple sclerosis — a longitudinal voxel-based morphometry study
Tools
Bendfeldt, Kerstin, Kuster, Pascal, Traud, Stefan, Egger, Hanspeter, Winklhofer, Sebastian, Mueller-Lenke, Nicole, Naegelin, Yvonne, Gass, Achim, Kappos, Ludwig, Matthews, Paul M., Nichols, Thomas E., Radue, E.-W. (Ernst-Wilhelm) and Borgwardt, Stefan. (2009) Association of regional gray matter volume loss and progression of white matter lesions in multiple sclerosis — a longitudinal voxel-based morphometry study. NeuroImage, Vol.45 (No.1). pp. 60-67. ISSN 1053-8119
Full text not available from this repository.
Official URL: http://dx.doi.org/10.1016/j.neuroimage.2008.10.006
Abstract
Previous studies have established regional gray matter (GM) volume loss in multiple sclerosis (MS) but the relationship between development of white matter (WM) lesions and changes of regional GM volumes is unclear. The present study addresses this issue by means of voxel-based morphometry (VBM).
| Item Type: | Journal Article |
|---|---|
| Subjects: | Q Science > QA Mathematics R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry |
| Divisions: | Faculty of Science > Statistics Faculty of Science > WMG (Formerly the Warwick Manufacturing Group) |
| Library of Congress Subject Headings (LCSH): | Magnetic resonance imaging, Longitudinal method, Multiple sclerosis -- Magnetic resonance imaging, Brain -- Degeneration |
| Journal or Publication Title: | NeuroImage |
| Publisher: | Elsevier |
| ISSN: | 1053-8119 |
| Date: | March 2009 |
| Volume: | Vol.45 |
| Number: | No.1 |
| Number of Pages: | 8 |
| Page Range: | pp. 60-67 |
| Identification Number: | 10.1016/j.neuroimage.2008.10.006 |
| Status: | Peer Reviewed |
| Publication Status: | Published |
| Access rights to Published version: | Open Access |
| References: | Amato, M.P., Bartolozzi, M.L., Zipoli, V., Portaccio, E., Mortilla, M., Guidi, L., Siracusa, G., Sorbi, S., Federico, A.,De Stefano, N., 2004. Neocortical volume decrease in relapsingremitting MS patients with mild cognitive impairment. Neurology 63, 89–93. Anderson, V.M., 2006. Magnetic resonance imaging measures of brain atrophy in multiple sclerosis. J. Magn. Reson. Imaging 23, 605–618. Ashburner, J., Friston, K.J., 2000. Voxel-based morphometry—the methods. NeuroImage 11, 805–821. Audoin, B., Davies, G.R., Finisku, L., Chard, D.T., Thompson, A.J., Miller, D.H., 2006. Localization of grey matter atrophy in early RRMS. J. Neurol. 253, 1495–1501. Borgwardt, S.J., McGuire, P.K., Aston, J., Berger, G., Dazzan, P., Gschwandtner, U., Pfluger, M., D'Souza, M., Radue, E.W., Riecher-Rossler, A., 2007a. Structural brain abnormalities in individuals with an at-risk mental state who later develop psychosis. Br. J. Psychiatry Suppl. 51, s69–s75. Borgwardt, S.J., Riecher-Rossler, A., Dazzan, P., Chitnis, X., Aston, J., Drewe, M., Gschwandtner, U., Haller, S., Pfluger, M., Rechsteiner, E., D'Souza, M., Stieglitz, R.-D., Radu, E.-W., McGuire, P.K., 2007b. Regional gray matter volume abnormalities in the at risk mental state. Biol. Psychiatry 61, 1148–1156. Borgwardt, S.J., McGuire, P., Fusar-Poli, P., Radue, E.W., Riecher-Rossler, A., 2008a. Anterior cingulate pathology in the prodromal stage of schizophrenia. NeuroImage 39, 553–554. Borgwardt, S.J., McGuire, P., Aston, J., Gschwandtner, U., Pflueger, M., Stieglitz, R.D., Radue, E.W., Riecher-Rössler, A., 2008b. Reductions in frontal, temporal and parietal volume associated with the onset of psychsis. Schizophrenia Research 106 (2–3), 20–26. Brambati, S.M., Renda, N.C., Rankin, K.P., Rosen, H.J., Seeley,W.W., Ashburner, J.,Weiner, M.W., Miller, B.L., Gorno-Tempini, M.L., 2007. A tensor based morphometry study of longitudinal gray matter contraction in FTD. NeuroImage 35, 998–1003. Ceccarelli, A., Rocca, M.A., Pagani, E., Colombo, B., Martinelli, V., Comi, G., Filippi, M., 2008. A voxel-based morphometry study of grey matter loss in MS patients with different clinical phenotypes. NeuroImage 42, 315–322. Chard, D.T., Griffin, C.M., Parker, G.J.M., Kapoor, R., Thompson, A.J., Miller, D.H., 2002. Brain atrophy in clinically early relapsing-remitting multiple sclerosis. Brain 125, 327–337. Chard, D.T., Griffin, C.M., Rashid, W., Davies, G.R., Altmann, D.R., Kapoor, R., Barker, G.J., Thompson, A.J., Miller, D.H., 2004. Progressive grey matter atrophy in clinically early relapsing-remitting multiple sclerosis. Mult. Scler. 10, 387–391. Charil, A., Dagher, A., Lerch, J.P., Zijdenbos, A.P., Worsley, K.J., Evans, A.C., 2007. Focal cortical atrophy in multiple sclerosis: relation to lesion load and disability. NeuroImage 34, 509–517. Chen, J.T., Narayanan, S., Collins, D.L., Smith, S.M., Matthews, P.M., Arnold, D.L., 2004. Relating neocortical pathology to disability progression in multiple sclerosis using MRI. NeuroImage 23, 1168–1175. Dalton, C.M., Chard, D.T., Davies, G.R., Miszkiel, K.A., Altmann, D.R., Fernando, K., Plant, G.T., Thompson, A.J., Miller, D.H., 2004. Early development of multiple sclerosis is associated with progressive grey matter atrophy in patients presenting with clinically isolated syndromes. Brain 127, 1101–1107. De Stefano, N., Matthews, P.M., Filippi, M., Agosta, F., De Luca, M., Bartolozzi, M.L., Guidi, L., Ghezzi, A., Montanari, E., Cifelli, A., Federico, A., Smith, S.M., 2003. Evidence of early cortical atrophy in MS: relevance to white matter changes and disability. Neurology 60, 1157–1162. Evangelou, N., Konz, D., Esiri, M.M., Smith, S., Palace, J., Matthews, P.M., 2000. Regional axonal loss in the corpus callosum correlates with cerebral white matter lesion volume and distribution in multiple sclerosis. Brain 123, 1845–1849. Fox, N.C., Jenkins, R., Leary, S.M., Stevenson, V.L., Losseff, N.A., Crum, W.R., Harvey, R.J., Rossor, M.N., Miller, D.H., Thompson, A.J., 2000. Progressive cerebral atrophy in MS: a serial study using registered, volumetric MRI. Neurology 54, 807–812. Fusar-Poli, P., Perez, J., Broome, M., Borgwardt, S., Placentino, A., Caverzasi, E., Cortesi, M., Veggiotti, P., Politi, P., Barale, F., McGuire, P., 2007. Neurofunctional correlates of vulnerability to psychosis: a systematic review and meta-analysis. Neurosci. Biobehav. Rev. 31, 465–484. Ge, Y., Grossman, R.I., Udupa, J.K., Wei, L., Mannon, L.J., Polansky, M., Kolson, D.L., 2000. Brain atrophy in relapsing-remitting multiple sclerosis and secondary progressive multiple sclerosis: longitudinal quantitative analysis. Radiology 214, 665–670. Ge, Y., Grossman, R.I., Udupa, J.K., Babb, J.S., Nyul, L.G., Kolson, D.L., 2001. Brain atrophy in relapsing-remitting multiple sclerosis: fractional volumetric analysis of gray matter and white matter. Radiology 220, 606–610. Good, C.D., Johnsrude, I.S., Ashburner, J., Henson, R.N.A., Friston, K.J., Frackowiak, R.S.J., 2001. A voxel-based morphometric study of ageing in 465 normal adult human brains. NeuroImage 14, 21–36. Hardmeier, M., Wagenpfeil, S., Freitag, P., Fisher, E., Rudick, R.A., Kooijmans- Coutinho, M., Clanet, M., Radue, E.W., Kappos, L., 2003. Atrophy is detectable within a 3-month period in untreated patients with active relapsing remitting multiple sclerosis. Arch. Neurol. 60, 1736–1739. Hayasaka, S., Phan, K.L., Liberzon, I., Worsley, K.J., Nichols, T.E., 2004. Nonstationary cluster-size inference with random field and permutation methods. NeuroImage 22, 676–687. Kalkers, N.F., Ameziane, N., Bot, J.C.J., Minneboo, A., Polman, C.H., Barkhof, F., 2002. Longitudinal brain volume measurement in multiple sclerosis: rate of brain atrophy is independent of the disease subtype. Arch. Neurol. 59, 1572–1576. Kappos, L., Antel, J., Comi, G., Montalban, X., O'Connor, P., Polman, C.H., Haas, T., Korn, A.A., Karlsson, G., Radue, E.W., the, F.T.Y.D.S.G., 2006. Oral fingolimod (FTY720) for relapsing multiple sclerosis. N. Engl. J. Med. 355, 1124–1140. Kipps, C.M., Duggins, A.J., Mahant, N., Gomes, L., Ashburner, J., McCusker, E.A., 2005. Progression of structural neuropathology in preclinical Huntington's disease: a tensor based morphometry study. J. Neurol. Neurosurg. Psychiatry 76, 650–655. Kutzelnigg, A., Lassmann, H., 2005. Cortical lesions and brain atrophy in MS. J. Neurol. Sci. 233, 55–59. Leow, A.D., Klunder, A.D., Jack Jr., C.R., Toga, A.W., Dale, A.M., Bernstein, M.A., Britson, P.J., Gunter, J.L., Ward, C.P., Whitwell, J.L., Borowski, B.J., Fleisher, A.S., Fox, N.C., Harvey, D., Kornak, J., Schuff, N., Studholme, C., Alexander, G.E., Weiner, M.W., Thompson, P.M., 2006. Longitudinal stability of MRI for mapping brain change using tensor-based morphometry. NeuroImage 31, 627–640. Lin, X., Blumhardt, L.D., 2001. Inflammation and atrophy in multiple sclerosis: MRI associations with disease course. J. Neurol. Sci. 189, 99–104. McDonald, W.I., Compston, A., Edan, G., Goodkin, D., Hartung, H.P., Lublin, F.D., McFarland, H.F., Paty, D.W., Polman, C.H., Reingold, S.C., Sandberg-Wollheim, M., Sibley, W., Thompson, A., van den Noort, S., Weinshenker, B.Y., Wolinsky, J.S., 2001. Recommended diagnostic criteria for multiple sclerosis: guidelines from the International Panel on the diagnosis of multiple sclerosis. Ann. Neurol. 50, 121–127. Miller, D.H., Barkhof, F., Frank, J.A., Parker, G.J.M., Thompson, A.J., 2002. Measurement of atrophy in multiple sclerosis: pathological basis, methodological aspects and clinical relevance. Brain 125, 1676–1695. Molyneux, P.D., Kappos, L., Polman, C., Pozzilli, C., Barkhof, F., Filippi, M., Yousry, T., Hahn, D., Wagner, K., Ghazi, M., Beckmann, K., Dahlke, F., Losseff, N., Barker, G.J., Thompson, A.J., Miller, D.H., 2000. The effect of interferon beta-1b treatment on MRI measures of cerebral atrophy in secondary progressive multiple sclerosis. Brain 123, 2256–2263. Moorhead, T.W.J., Job, D.E., Spencer, M.D., Whalley, H.C., Johnstone, E.C., Lawrie, S.M., 2005. Empirical comparison of maximal voxel and non-isotropic adjusted cluster extent results in a voxel-based morphometry study of comorbid learning disability with schizophrenia. NeuroImage 28, 544–552. Morgen, K., Sammer, G., Courtney, S.M., Wolters, T., Melchior, H., Blecker, C.R., Oschmann, P., Kaps, M., Vaitl, D., 2006. Evidence for a direct association between cortical atrophy and cognitive impairment in relapsing-remitting MS. NeuroImage 30, 891–898. Pagani, E., Rocca, M.A., Gallo, A., Rovaris, M., Martinelli, V., Comi, G., Filippi, M., 2005. Regional brain atrophy evolves differently in patients with multiple sclerosis according to clinical phenotype. AJNR Am. J. Neuroradiol. 26, 341–346. Pirko, I., Lucchinetti, C.F., Sriram, S., Bakshi, R., 2007. Gray matter involvement in multiple sclerosis. Neurology 68, 634–642. Prinster, A., Quarantelli, M., Orefice, G., Lanzillo, R., Brunetti, A., Mollica, C., Salvatore, E., Morra, V.B., Coppola, G., Vacca, G., Alfano, B., Salvatore, M., 2006. Grey matter loss inrelapsing-remitting multiple sclerosis: a voxel-based morphometry study. Neuro- Image 29, 859–867. Quarantelli, M., Ciarmiello, A., Morra, V.B., Orefice, G., Larobina,M., Lanzillo, R., Schiavone, V., Salvatore, E., Alfano, B., Brunetti, A., 2003. Brain tissue volume changes in relapsingremitting multiple sclerosis: correlation with lesion load. NeuroImage 18, 360–366. Rovaris, M., Comi, G., Rocca, M.A., Wolinsky, J.S., Filippi, M., 2001. Short-term brain volume change in relapsing-remitting multiple sclerosis: effect of glatiramer acetate and implications. Brain 124, 1803–1812. Rudick, R.A., Fisher, E., Lee, J.C., Simon, J., Jacobs, L., 1999. Use of the brain parenchymal fraction to measure whole brain atrophy in relapsing-remitting MS. Neurology 53, 1698–1704. Sailer, M., Fischl, B., Salat, D., Tempelmann, C., Schonfeld, M.A., Busa, E., Bodammer, N., Heinze, H.-J., Dale, A., 2003. Focal thinning of the cerebral cortex in multiple sclerosis. Brain 126, 1734–1744. Sanfilipo, M.P., Benedict, R.H.B., Sharma, J.,Weinstock-Guttman, B., Bakshi, R., 2005. The relationship between whole brain volume and disability in multiple sclerosis: a comparison of normalized gray vs. white matter with misclassification correction. NeuroImage 26, 1068–1077. Sanfilipo, M.P., Benedict, R.H.B.,Weinstock-Guttman, B., Bakshi, R., 2006. Gray and white matter brain atrophy and neuropsychological impairment in multiple sclerosis. Neurology 66, 685–692. Schmahmann, J.D., Doyon, J., McDonald, D., Holmes, C., Lavoie, K., Hurwitz, A.S., Kabani, N., Toga, A., Evans, A., Petrides, M., 1999. Three-dimensional MRI atlas of the human cerebellum in proportional stereotaxic space. NeuroImage 10, 233–260. Sepulcre, J., Sastre-Garriga, J., Cercignani, M., Ingle, G.T., Miller, D.H., Thompson, A.J., 2006. Regional gray matter atrophy in early primary progressive multiple sclerosis: a voxel-based morphometry study. Arch. Neurol. 63, 1175–1180. Talairach, J., Tournoux, P., 1998. Co-planar stereotaxic atlas of the human brain. Thieme Medical Publishers, New York. Tiberio, M., Chard, D.T., Altmann, D.R., Davies, G., Griffin, C.M., Rashid, W., Sastre- Garriga, J., Thompson, A.J., Miller, D.H., 2005. Gray and white matter volume changes in early RRMS: a 2-year longitudinal study. Neurology 64, 1001–1007. Trapp, B.D., Nave, K.-A., 2008. Multiple sclerosis: an immune or neurodegenerative disorder? Annu. Rev. Neurosci. 31, 247–269. White, T., O'Leary, D., Magnotta, V., Arndt, S., Flaum, M., Andreasen, N.C., 2001. Anatomic and functional variability: the effects of filter size in group fMRI data analysis. NeuroImage 13, 577–588. Zivadinov, R., Sepcic, J., Nasuelli, D., De Masi, R., Bragadin, L.M., Tommasi, M.A., Zambito- Marsala, S., Moretti, R., Bratina, A., Ukmar, M., Pozzi-Mucelli, R.S., Grop, A., Cazzato, G., Zorzon, M., 2001. A longitudinal study of brain atrophy and cognitive disturbances in the early phase of relapsing-remitting multiple sclerosis. J. Neurol. Neurosurg. Psychiatry 70, 773–780. |
| URI: | http://wrap.warwick.ac.uk/id/eprint/41129 |
Data sourced from Thomson Reuters' Web of Knowledge
Actions (login required)
![]() |
View Item |
Tools
Tools

