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Fluorescently labeled protein-polymer bioconjugates using protein-derived macroinitiators from living radical polymerization

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Nicolas, Julien, Miguel, V. , Manovani, G. and Haddleton, David M. (2008) Fluorescently labeled protein-polymer bioconjugates using protein-derived macroinitiators from living radical polymerization. In: International Symposium on Polymers for Biomedical Applications/232nd National Meeting of the American-Chemical-Society (ACS), San Francisco, CA, 10-14 Sep 2006 . Published in: Polymers for Biomedical Applications, Vol.977 pp. 78-94.

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Abstract

Bovine Serum Albumin (BSA) and lysozyme have been chemically transformed into macroinitiators for the synthesis of fluorescent bioconjugates by living radical polymerization. A new fluorescent monomer based on rhodamine B has been synthesized and incorporated into the polymer backbone of the bioconjugate by copolymerization. This provides a new strategy for the synthesis of fluorescent bioconjugates with improved traceability in biological environments, during biomedical assays

Item Type: Conference Item (Paper)
Divisions: Faculty of Science > Chemistry
Journal or Publication Title: Polymers for Biomedical Applications
Publisher: American Chemical Society
ISSN: 0097-6156
Date: 2008
Volume: Vol.977
Page Range: pp. 78-94
Status: Peer Reviewed
Publication Status: Published
Conference Paper Type: Paper
Title of Event: International Symposium on Polymers for Biomedical Applications/232nd National Meeting of the American-Chemical-Society (ACS)
Type of Event: Conference
Location of Event: San Francisco, CA
Date(s) of Event: 10-14 Sep 2006
URI: http://wrap.warwick.ac.uk/id/eprint/41423

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