Hand pattern indicates prostate cancer risk
Rahman, A. A., Lophatananon, Artitaya, Stewart-Brown, Sarah L., Harriss, D., Anderson, J., Parker, Terence, Easton, Douglas F., Kote-Jarai, Zsofia, Pocock, Richard D., Dearnaley, David, Guy, M., O'Brien, Lynne, Wilkinson, Rosemary A., Hall, Amanda L., Sawyer, Elinor, Page, Elizabeth C., Liu, Jo-Fen, Eeles, Rosalind A. and Muir, Kenneth. (2011) Hand pattern indicates prostate cancer risk. British Journal of Cancer, Volume 104 (Number 1). pp. 175-177. ISSN 0007-0920Full text not available from this repository.
Official URL: http://dx.doi.org/10.1038/sj.bjc.6605986
BACKGROUND: The ratio of digit lengths is fixed in utero, and may be a proxy indicator for prenatal testosterone levels.
METHODS: We analysed the right-hand pattern and prostate cancer risk in 1524 prostate cancer cases and 3044 population-based controls.
RESULTS: Compared with index finger shorter than ring finger (low 2D : 4D), men with index finger longer than ring finger (high 2D : 4D) showed a negative association, suggesting a protective effect with a 33% risk reduction (odds ratio (OR) 0.67, 95% confidence interval (CI) 0.57-0.80). Risk reduction was even greater (87%) in age group <60 (OR 0.13, 95% CI 0.09-0.21).
CONCLUSION: Pattern of finger lengths may be a simple marker of prostate cancer risk, with length of 2D greater than 4D suggestive of lower risk. British Journal of Cancer (2011) 104, 175-177. doi:10.1038/sj.bjc.6605986 www.bjcancer.com Published online 30 November 2010 (C) 2011 Cancer Research UK
|Item Type:||Journal Article|
|Subjects:||R Medicine > RC Internal medicine > RC0254 Neoplasms. Tumors. Oncology (including Cancer)|
|Divisions:||Faculty of Medicine > Warwick Medical School > Health Sciences
Faculty of Medicine > Warwick Medical School > Mental Health and Wellbeing
Faculty of Medicine > Warwick Medical School
|Library of Congress Subject Headings (LCSH):||Prostate -- Cancer -- Risk factors, Prostate -- Cancer -- Epidemiology|
|Journal or Publication Title:||British Journal of Cancer|
|Publisher:||Nature Publishing Group|
|Official Date:||4 January 2011|
|Page Range:||pp. 175-177|
|Access rights to Published version:||Restricted or Subscription Access|
|Funder:||Prostate Cancer Research Foundation, Cancer Research UK (CRUK), Royal Marsden NHS Foundation Trust, National Institute for Health Research (Great Britain) (NIHR)|
|Grant number:||C5047/A8385 (CRUK)|
|Version or Related Resource:||Cheema, M., Sharif, A. (2011) Comment on ‘Hand pattern indicates risk of prostate cancer’. Br J Cancer, 105, p. 466. ; Rahman, A. A., Lophatananon, A., Stewart-Brown, S., et al. (2011). Reply : ‘Hand pattern indicates risk of prostate cancer’. British Journal of Cancer, 105(3), pp. 467-467. http://wrap.warwick.ac.uk/id/eprint/38664|
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