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Hand pattern indicates prostate cancer risk
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Rahman, A. A., Lophatananon, Artitaya, Stewart-Brown, Sarah L., Harriss, D., Anderson, J., Parker, T., Easton, D., Kote-Jarai, Z., Pocock, R., Dearnaley, D., Guy, M., O'Brien, L., Wilkinson, R. A., Hall, A. L., Sawyer, E., Page, E., Liu, J. -F., Eeles, R. A. and Muir, Kenneth (Kenneth R.). (2011) Hand pattern indicates prostate cancer risk. British Journal of Cancer, Vol.104 (No.1). pp. 175-177. ISSN 0007-0920
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Official URL: http://dx.doi.org/10.1038/sj.bjc.6605986
Abstract
BACKGROUND: The ratio of digit lengths is fixed in utero, and may be a proxy indicator for prenatal testosterone levels. METHODS: We analysed the right-hand pattern and prostate cancer risk in 1524 prostate cancer cases and 3044 population-based controls. RESULTS: Compared with index finger shorter than ring finger (low 2D : 4D), men with index finger longer than ring finger (high 2D : 4D) showed a negative association, suggesting a protective effect with a 33% risk reduction (odds ratio (OR) 0.67, 95% confidence interval (CI) 0.57-0.80). Risk reduction was even greater (87%) in age group <60 (OR 0.13, 95% CI 0.09-0.21). CONCLUSION: Pattern of finger lengths may be a simple marker of prostate cancer risk, with length of 2D greater than 4D suggestive of lower risk. British Journal of Cancer (2011) 104, 175-177. doi:10.1038/sj.bjc.6605986 www.bjcancer.com Published online 30 November 2010 (C) 2011 Cancer Research UK
| Item Type: | Journal Article |
|---|---|
| Subjects: | R Medicine > RC Internal medicine > RC0254 Neoplasms. Tumors. Oncology (including Cancer) |
| Divisions: | Faculty of Medicine > Warwick Medical School > Health Sciences Faculty of Medicine > Warwick Medical School > Mental Health and Wellbeing Faculty of Medicine > Warwick Medical School |
| Journal or Publication Title: | British Journal of Cancer |
| Publisher: | Nature Publishing Group |
| ISSN: | 0007-0920 |
| Date: | 4 January 2011 |
| Volume: | Vol.104 |
| Number: | No.1 |
| Page Range: | pp. 175-177 |
| Identification Number: | 10.1038/sj.bjc.6605986 |
| Status: | Peer Reviewed |
| Publication Status: | Published |
| Access rights to Published version: | Restricted or Subscription Access |
| Funder: | Prostate Cancer Research Foundation, Cancer Research UK , National Institute for Health Research (NIHR), Royal Marsden NHS Foundation Trust |
| Grant number: | C5047/A8385 (Cancer Research UK) |
| URI: | http://wrap.warwick.ac.uk/id/eprint/41675 |
Data sourced from Thomson Reuters' Web of Knowledge
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