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Modelling the rate of change in a longitudinal study with missing data, adjusting for contact attempts

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Akacha, Mouna and Hutton, Jane L.. (2011) Modelling the rate of change in a longitudinal study with missing data, adjusting for contact attempts. Statistics in Medicine, Vol.30 (No.10). pp. 1072-1089. ISSN 0277-6715

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Official URL: http://dx.doi.org/10.1002/sim.4165

Abstract

The Collaborative Ankle Support Trial (CAST) is a longitudinal trial of treatments for severe ankle sprains in which interest lies in the rate of improvement, the effectiveness of reminders and potentially informative missingness. A model is proposed for continuous longitudinal data with non-ignorable or informative missingness, taking into account the nature of attempts made to contact initial non-responders. The model combines a non-linear mixed model for the outcome model with logistic regression models for the reminder processes. A sensitivity analysis is used to contrast this model with the traditional selection model, where we adjust for missingness by modelling the missingness process. The conclusions that recovery is slower, and less satisfactory with age and more rapid with below knee cast than with a tubular bandage do not alter materially across all models investigated. The results also suggest that phone calls are most effective in retrieving questionnaires. Copyright (C) 2011 John Wiley & Sons, Ltd.

Item Type: Journal Article
Subjects: Q Science > QA Mathematics
R Medicine > R Medicine (General)
Divisions: Faculty of Science > Statistics
Series Name: Working papers
Journal or Publication Title: Statistics in Medicine
Publisher: John Wiley & Sons Ltd.
Place of Publication: Coventry
ISSN: 0277-6715
Date: 10 May 2011
Volume: Vol.30
Number: No.10
Page Range: pp. 1072-1089
Identification Number: 10.1002/sim.4165
Status: Peer Reviewed
Publication Status: Published
Access rights to Published version: Restricted or Subscription Access
URI: http://wrap.warwick.ac.uk/id/eprint/41753

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  • Modelling the rate of change in a longitudinal study with missing data, adjusting for contact attempts. (deposited 08 Jun 2011 14:37)
    • Modelling the rate of change in a longitudinal study with missing data, adjusting for contact attempts. (deposited 15 Feb 2012 12:10) [Currently Displayed]

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