Healey, E. L., Haywood, Kirstie L., Jordan, K. P., Garratt, A. M. and Packham, J. C.. (2010) Disease severity in ankylosing spondylitis : variation by region and local area deprivation. Journal of Rheumatology, Vol.37 (No.3). pp. 633-638. ISSN 0315-162X

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Abstract

Objective. To investigate whether patient disease severity in ankylosing spondylitis (AS) varies among regions or by local area social deprivation. Methods. Eight hundred patients with AS from 8 specialist rheumatology centers across England were invited to participate in a cross-sectional survey. Sociodemographic and disease-related variables were collected [pain (numerical rating scale), disease activity (Bath AS Disease Activity Index), and physical function (Bath AS Functional Index)]. Deprivation was measured using the Index of Multiple Deprivation 2004. Results. Of the 800 patients invited, 468 responded (adjusted response rate 62.8%). Most were male (72.9%), with a mean age of 50.2 years (SD 12.1), and a mean diagnosed disease duration of 17 years (SD 11.4). Across all centers, those living in more deprived areas demonstrated significantly greater disease severity and poorer psychological health. After controlling for age, gender, disease duration, and region, greater deprivation was significantly associated with greater disease activity (OR 3.39; 95% CI 1.65, 6.98) and poorer function (OR 4.46; 95% CI 2.11, 9.44). There was a nonsignificant trend toward more pain (OR 1.98; 95% CI 0.97, 4.07). There was also a significant independent association between region and disease severity. Conclusion. The need for healthcare is greatest for patients with AS who are living in more socially deprived areas. With the growing use of interventional therapies, these findings have important implications if health service resources are to be allocated equitably; particularly as deprived patients are known to access healthcare less frequently.

Item Type:	Journal Article
Subjects:	R Medicine > R Medicine (General)
Divisions:	Faculty of Social Sciences > School of Health and Social Studies
Journal or Publication Title:	Journal of Rheumatology
Publisher:	Journal of Rheumatology Publishing Co. Ltd.
ISSN:	0315-162X
Date:	March 2010
Volume:	Vol.37
Number:	No.3
Page Range:	pp. 633-638
Identification Number:	10.3899/jrheum.090899
Status:	Peer Reviewed
Publication Status:	Published
Access rights to Published version:	Restricted or Subscription Access
URI:	http://wrap.warwick.ac.uk/id/eprint/42147

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