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A novel framework for molecular co-expression pattern analysis in multi-channel toponome fluorescence images
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Humayun, A., Raza, Shan-e-Ahmed, Waddington, C., Abouna, Sylvie, Khan, Michael and Rajpoot, Nasir M. (Nasir Mahmood) (2011) A novel framework for molecular co-expression pattern analysis in multi-channel toponome fluorescence images. In: MIAAB 2011 (Microscopic Image Analysis with Applications in Biology), Heidelberg, Germany, 2 Sep 2011. Published in: Proceedings of the 2011 Microscopic Image Analysis with Applications in Biology (Submitted)
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Official URL: http://www.miaab.org/miaab-2011-heidelberg-papers....
Abstract
Bioimage computing is rapidly emerging as an
important area in image based systems biology with an emphasis on spatiotemporal localization of subcellular bio-molecules, most importantly proteins. A key problem in this domain is analysis of protein co-localization or co expression of protein molecules.
Imaging techniques, such as the Toponome Imaging System
(TIS) [1], with the ability to localize several different proteins in the same tissue specimen are only becoming available recently. Traditional co-localization studies and some of the modern coexpression studies have serious limitations when analyzing this kind of data. Here we present a framework for the analysis of molecular co-expression patterns (MCEPs) in TIS image data
Item Type: | Conference Item (Paper) | ||||
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Subjects: | Q Science > Q Science (General) | ||||
Divisions: | Faculty of Science, Engineering and Medicine > Science > Computer Science Faculty of Science, Engineering and Medicine > Science > Life Sciences (2010- ) |
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Journal or Publication Title: | Proceedings of the 2011 Microscopic Image Analysis with Applications in Biology | ||||
Official Date: | 2 September 2011 | ||||
Dates: |
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Status: | Peer Reviewed | ||||
Publication Status: | Submitted | ||||
Conference Paper Type: | Paper | ||||
Title of Event: | MIAAB 2011 (Microscopic Image Analysis with Applications in Biology) | ||||
Type of Event: | Workshop | ||||
Location of Event: | Heidelberg, Germany | ||||
Date(s) of Event: | 2 Sep 2011 |
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