Parsons, Nick, Friede, Tim, Todd, Susan and Stallard, Nigel (2011) Software tools for implementing simulation studies in adaptive seamless designs : introducing R package ASD. Trials, Vol.12 (Suppl.1). A8. ISSN 1745-6215

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Abstract

Adaptive designs for clinical trials have the potential to improve the efficiency of clinical research by, for instance, seamlessly combining different stages of a clinical development programme.

Item Type:	Journal Item
Subjects:	R Medicine > R Medicine (General)
Divisions:	Faculty of Medicine > Warwick Medical School
Library of Congress Subject Headings (LCSH):	Clinical trials -- Design, Clinical trials -- Computer simulation
Journal or Publication Title:	Trials
Publisher:	Bio Med Central
ISSN:	1745-6215
Date:	13 December 2011
Volume:	Vol.12
Number:	Suppl.1
Page Range:	A8
Identification Number:	10.1186/1745-6215-12-S1-A8
Status:	Peer Reviewed
Publication Status:	Published
Access rights to Published version:	Open Access
Description:	Poster presentation at Clinical Trials Methodology Conference 2011, Bristol, UK. 4-5 October 2011
References:	1. Parsons N, Friede T, Todd S, Valdes-Marquez E, Chataway J, Nicholas R, Stallard N: An R package for implementing simulations for seamless phase II/III clinical trials using early outcomes for treatment selection. Comput Stat Data An . 2. Friede T, Parsons N, Stallard N, Todd S, Valdes-Marquez E, Chataway J, Nicholas R: Designing a seamless phase II/III clinical trial using early outcomes for treatment selection: an application in multiple sclerosis. Stat Med 2011, 30:1528-1540.
URI:	http://wrap.warwick.ac.uk/id/eprint/42347

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