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Detection of Staphylococcus aureus cell walls by enzyme-linked immunoassay using antibodies prepared from a semi-synthetic peptidoglycan precursor
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Sandhu, Sandeep, Schouten, James A., Thompson, Julie, Davis, Mark and Bugg, Tim (2012) Detection of Staphylococcus aureus cell walls by enzyme-linked immunoassay using antibodies prepared from a semi-synthetic peptidoglycan precursor. The Analyst, Vol.137 (No.5). pp. 1130-1136. doi:10.1039/c2an16036f
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Official URL: http://dx.doi.org/10.1039/C2AN16036F
Abstract
The peptidoglycan layer of Staphylococcus aureus contains a (Gly)5 cross-link which is not found in other bacteria, and which could be used to develop a specific immunoassay for detection of S. aureus in MRSA infections. A semi-synthetic route was used to prepare the S. aureus peptidoglycan precursor UDPMurNAc-l-Al
| Item Type: | Journal Article | ||||
|---|---|---|---|---|---|
| Subjects: | Q Science > QD Chemistry | ||||
| Divisions: | Faculty of Science > Chemistry | ||||
| Journal or Publication Title: | The Analyst | ||||
| Publisher: | Royal Society of Chemistry | ||||
| ISSN: | 0003-2654 | ||||
| Official Date: | 7 March 2012 | ||||
| Dates: |
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| Volume: | Vol.137 | ||||
| Number: | No.5 | ||||
| Page Range: | pp. 1130-1136 | ||||
| DOI: | 10.1039/c2an16036f | ||||
| Status: | Peer Reviewed | ||||
| Publication Status: | Published | ||||
| Access rights to Published version: | Restricted or Subscription Access |
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