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Detection of Staphylococcus aureus cell walls by enzyme-linked immunoassay using antibodies prepared from a semi-synthetic peptidoglycan precursor
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Sandhu, Sandeep, Schouten, James A., Thompson, Julie, Davis, Mark and Bugg, Tim (2012) Detection of Staphylococcus aureus cell walls by enzyme-linked immunoassay using antibodies prepared from a semi-synthetic peptidoglycan precursor. The Analyst, Vol.137 (No.5). pp. 1130-1136. doi:10.1039/c2an16036f ISSN 0003-2654.
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Official URL: http://dx.doi.org/10.1039/C2AN16036F
Abstract
The peptidoglycan layer of Staphylococcus aureus contains a (Gly)5 cross-link which is not found in other bacteria, and which could be used to develop a specific immunoassay for detection of S. aureus in MRSA infections. A semi-synthetic route was used to prepare the S. aureus peptidoglycan precursor UDPMurNAc-l-Al
Item Type: | Journal Article | ||||
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Subjects: | Q Science > QD Chemistry | ||||
Divisions: | Faculty of Science, Engineering and Medicine > Science > Chemistry | ||||
Journal or Publication Title: | The Analyst | ||||
Publisher: | Royal Society of Chemistry | ||||
ISSN: | 0003-2654 | ||||
Official Date: | 7 March 2012 | ||||
Dates: |
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Volume: | Vol.137 | ||||
Number: | No.5 | ||||
Page Range: | pp. 1130-1136 | ||||
DOI: | 10.1039/c2an16036f | ||||
Status: | Peer Reviewed | ||||
Publication Status: | Published | ||||
Access rights to Published version: | Restricted or Subscription Access |
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