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Detection of Staphylococcus aureus cell walls by enzyme-linked immunoassay using antibodies prepared from a semi-synthetic peptidoglycan precursor

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Sandhu, Sandeep, Schouten, James A., Thompson, Julie, Davis, Mark and Bugg, Tim (2012) Detection of Staphylococcus aureus cell walls by enzyme-linked immunoassay using antibodies prepared from a semi-synthetic peptidoglycan precursor. The Analyst, Vol.137 (No.5). pp. 1130-1136. doi:10.1039/c2an16036f

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Official URL: http://dx.doi.org/10.1039/C2AN16036F

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Abstract

The peptidoglycan layer of Staphylococcus aureus contains a (Gly)5 cross-link which is not found in other bacteria, and which could be used to develop a specific immunoassay for detection of S. aureus in MRSA infections. A semi-synthetic route was used to prepare the S. aureus peptidoglycan precursor UDPMurNAc-l-Al

Item Type: Journal Article
Subjects: Q Science > QD Chemistry
Divisions: Faculty of Science > Chemistry
Journal or Publication Title: The Analyst
Publisher: Royal Society of Chemistry
ISSN: 0003-2654
Official Date: 7 March 2012
Dates:
DateEvent
7 March 2012Published
Volume: Vol.137
Number: No.5
Page Range: pp. 1130-1136
DOI: 10.1039/c2an16036f
Status: Peer Reviewed
Publication Status: Published
Access rights to Published version: Restricted or Subscription Access

Data sourced from Thomson Reuters' Web of Knowledge

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