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Clinical effectiveness and cost-effectiveness of continuous subcutaneous insulin infusion for diabetes : systematic review and economic evaluation
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Cummins, E. (Ewen), Royle, Pamela, Snaith, Ailsa, Greene, A., Robertson, L., McIntyre, Linda and Waugh, Norman (2010) Clinical effectiveness and cost-effectiveness of continuous subcutaneous insulin infusion for diabetes : systematic review and economic evaluation. Health Technology Assessment, Vol.14 (No.11). pp. 1-208. doi:10.3310/hta14110
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Official URL: http://dx.doi.org/10.3310/hta14110
Abstract
Based on the totality of evidence, using observational studies to supplement the limited data from randomised trials against best MDI, CSII provides some advantages over MDI in T1DM for both children and adults. However, there was no evidence that CSII is better than analogue-based MDI in T2DM or in pregnancy. Further trials with larger numbers and longer durations comparing CSII and optimised MDI in adults, adolescents and children are needed. In addition, there should be a trial of CSII versus MDI with similar provision of structured education in both arms. A trial is also needed for pregnant women with pre-existing diabetes, to investigate using CSII to the best effect.
| Item Type: | Journal Article | ||||
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| Subjects: | R Medicine > RC Internal medicine | ||||
| Divisions: | Faculty of Medicine > Warwick Medical School > Health Sciences > Population, Evidence & Technologies (PET) > Warwick Evidence Faculty of Medicine > Warwick Medical School > Health Sciences Faculty of Medicine > Warwick Medical School |
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| Library of Congress Subject Headings (LCSH): | Diabetes -- Treatment, Insulin -- Therapeutic use | ||||
| Journal or Publication Title: | Health Technology Assessment | ||||
| Publisher: | NIHR Health Technology Assessment programme | ||||
| ISSN: | 1366-5278 | ||||
| Official Date: | February 2010 | ||||
| Dates: |
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| Volume: | Vol.14 | ||||
| Number: | No.11 | ||||
| Page Range: | pp. 1-208 | ||||
| DOI: | 10.3310/hta14110 | ||||
| Status: | Peer Reviewed | ||||
| Publication Status: | Published | ||||
| Access rights to Published version: | Open Access | ||||
| Funder: | NIHR Health Technology Assessment Programme (Great Britain) |
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