Connock, M., Cummins, E. (Ewen), Sutcliffe, Paul A., Court, Rachel A., Johnson, Rhona, Grove, Amy L., Ngianga-Bakwin, Kandala, Mohiuddin, Syed and Clarke, Aileen, 1955- (2011) Belimumab for the treatment of active autoantibody-positive systemic lupus erythematosus. [Report]

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Abstract

The manufacturer’s scope encompasses the clinical effectiveness and cost effectiveness of belimumab plus Standard of Care (SoC) relative to SoC alone, for the treatment of adults with active auto-antibody positive Systemic Lupus Erythematosus (SLE) and also for a subgroup of these patients who exhibit signs of high disease activity. According to the manufacturer’s scope and submission the population of greatest interest is the sub-group with high disease activity called the Target population. No subgroup is specified in the National Institute for Health and Clinical Excellence (NICE) scope. The Target population is a subgroup of the proposed licensed population; a decision on the manufacturer’s license application is awaited.

Item Type:	Report
Alternative Title:	Evidence review group report commissioned by the National Health Service Research & Development Programme on behalf of the National Institute for Health and Clinical Evidence
Subjects:	Q Science > QR Microbiology > QR180 Immunology R Medicine > RC Internal medicine
Divisions:	Faculty of Medicine > Warwick Medical School > Warwick Evidence Faculty of Medicine > Warwick Medical School
Library of Congress Subject Headings (LCSH):	Systemic lupus erythematosus -- Treatment, Monoclonal antibodies
Publisher:	National Institute for Health and Clinical Excellence (NICE)
Place of Publication:	London
Date:	30 September 2011
Number of Pages:	166
Status:	Peer Reviewed
Publication Status:	Published
Access rights to Published version:	Open Access
Funder:	NIHR Health Technology Assessment Programme (Great Britain)
Grant number:	10/73/01 (NIHR HTA)
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URI:	http://wrap.warwick.ac.uk/id/eprint/44419

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