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Effects of diabetes family history and exercise training on the expression of adiponectin and leptin and their receptors
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Moran, C. N., Barwell, N. D., Malkova, D., Cleland, S. J., McPhee, I., Packard, Christopher J., Zammit, V. A. (Victor A.) and Gill, J. M. R. (Jason M. R.). (2009) Effects of diabetes family history and exercise training on the expression of adiponectin and leptin and their receptors. Proceedings of the Nutrition Society, Vol.68 (No.OCE2). ISSN 0029-6651
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Official URL: http://dx.doi.org/10.1017/S002966510999036X
Abstract
The daughters of patients with diabetes have reduced insulin sensitivity index (ISI) scores compared with women with no family history of diabetes, but their ISI increase more in response to exercise training(1). The present study aimed to determine whether differences between these groups in exercise-induced changes in circulating adiponectin and leptin concentrations and expression of their genes and receptors in subcutaneous adipose tissue (SAT), could explain differences in the exercise-induced changes in ISI between women with and without a family history of diabetes.
| Item Type: | Journal Article |
|---|---|
| Subjects: | R Medicine > RC Internal medicine |
| Divisions: | Faculty of Medicine > Warwick Medical School > Clinical Sciences Research Institute (CSRI) Faculty of Medicine > Warwick Medical School > Metabolic and Vascular Health Faculty of Medicine > Warwick Medical School |
| Library of Congress Subject Headings (LCSH): | Non-insulin-dependent diabetes -- Genetic aspects, Non-insulin-dependent diabetes -- Susceptibility, Exercise -- Health aspects, Exercise -- Genetic aspects, Leptin |
| Journal or Publication Title: | Proceedings of the Nutrition Society |
| Publisher: | Cambridge University Press |
| ISSN: | 0029-6651 |
| Date: | April 2009 |
| Volume: | Vol.68 |
| Number: | No.OCE2 |
| Identification Number: | 10.1017/S002966510999036X |
| Status: | Peer Reviewed |
| Publication Status: | Published |
| Access rights to Published version: | Restricted or Subscription Access |
| References: | 1. Barwell ND, Malkova D, Moran CN et al. (2008) Diabetologia 51, 1912–1919. |
| URI: | http://wrap.warwick.ac.uk/id/eprint/4448 |
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