The Library
The growth restriction intervention trial : long-term outcomes in a randomized trial of timing of delivery in fetal growth restriction
Tools
Walker, Dawn-Marie, Marlow, Neil, Upstone, Lisa, Gross, Harriet, Dr., Hornbuckle, Janet, Vail, Andy, Wolke, Dieter and Thornton, Jim (Jim G.) (2011) The growth restriction intervention trial : long-term outcomes in a randomized trial of timing of delivery in fetal growth restriction. American Journal of Obstetrics and Gynecology, Vol.204 (No.1). 34.e1-34.e9. doi:10.1016/j.ajog.2010.09.019 ISSN 0002-9378.
Research output not available from this repository.
Request-a-Copy directly from author or use local Library Get it For Me service.
Official URL: http://dx.doi.org/10.1016/j.ajog.2010.09.019
Abstract
OBJECTIVE: The Growth Restriction Intervention Trial found little difference in overall mortality or 2-year outcomes associated with immediate or deferred delivery following signs of impaired fetal health in the presence of growth restriction when the obstetrician was unsure whether to deliver. Because early childhood assessments have limited predictive value, we reevaluated them.
STUDY DESIGN: Children were tested with standardized school-based evaluations of cognition, language, motor performance, and behavior. Analysis and interpretation were Bayesian.
RESULTS: Of 376 babies, 302 (80%) had known outcome: either dead or evaluated at age 6-13 years. Numbers of children dead, or with severe disability: 21 (14%) immediate and 25 (17%) deferred groups. Among survivors, the mean (SD) cognition scores were 95 (15) and 96 (14); motor scores were 8.9 (7.0) and 8.7 (6.7); and parent-assessed behavior scores were 10.5 (7.1) and 10.5 (6.9), respectively, for the 2 groups.
CONCLUSION: Clinically significant differences between immediate and deferred delivery were not found.
Item Type: | Journal Article | ||||
---|---|---|---|---|---|
Subjects: | R Medicine > RG Gynecology and obstetrics R Medicine > RJ Pediatrics |
||||
Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences > Mental Health and Wellbeing Faculty of Science, Engineering and Medicine > Science > Psychology Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School |
||||
Library of Congress Subject Headings (LCSH): | Fetal growth disorders, Cognition in children -- Research, Neuropsychology, Premature infants -- Development, Premature infants -- Death, Fetal growth retardation | ||||
Journal or Publication Title: | American Journal of Obstetrics and Gynecology | ||||
Publisher: | Mosby-Elsevier | ||||
ISSN: | 0002-9378 | ||||
Official Date: | January 2011 | ||||
Dates: |
|
||||
Volume: | Vol.204 | ||||
Number: | No.1 | ||||
Number of Pages: | 9 | ||||
Page Range: | 34.e1-34.e9 | ||||
DOI: | 10.1016/j.ajog.2010.09.019 | ||||
Status: | Peer Reviewed | ||||
Publication Status: | Published | ||||
Access rights to Published version: | Restricted or Subscription Access | ||||
Funder: | Medical Research Council (Great Britain) (MRC) | ||||
Version or Related Resource: | Presented at: 56th Annual Scientific Meeting of the Society of Gynecological Investigation, Glasgow UK, 18-21 Mar 2009 | ||||
Conference Paper Type: | Paper | ||||
Type of Event: | Conference |
Data sourced from Thomson Reuters' Web of Knowledge
Request changes or add full text files to a record
Repository staff actions (login required)
View Item |