Skip to content Skip to navigation
University of Warwick
  • Study
  • |
  • Research
  • |
  • Business
  • |
  • Alumni
  • |
  • News
  • |
  • About

University of Warwick
Publications service & WRAP

Highlight your research

  • WRAP
    • Home
    • Search WRAP
    • Browse by Warwick Author
    • Browse WRAP by Year
    • Browse WRAP by Subject
    • Browse WRAP by Department
    • Browse WRAP by Funder
    • Browse Theses by Department
  • Publications Service
    • Home
    • Search Publications Service
    • Browse by Warwick Author
    • Browse Publications service by Year
    • Browse Publications service by Subject
    • Browse Publications service by Department
    • Browse Publications service by Funder
  • Help & Advice
University of Warwick

The Library

  • Login
  • Admin

Insights into ‘fermentonomics’ : evaluation of volatile organic compounds (VOCs) in human disease using an electronic ‘e-nose’

Tools
- Tools
+ Tools

Arasaradnam, Ramesh P., Quraishi, N., Kyrou, I., Nwokolo, Chuka U., Joseph, M., Kumar, Sudhesh, Bardhan, Karna Dev and Covington, James A. (2011) Insights into ‘fermentonomics’ : evaluation of volatile organic compounds (VOCs) in human disease using an electronic ‘e-nose’. Journal of Medical Engineering & Technology, Vol.35 (No.2). pp. 87-91. doi:10.3109/03091902.2010.539770

Research output not available from this repository, contact author.
Official URL: http://dx.doi.org/10.3109/03091902.2010.539770

Request Changes to record.

Abstract

Detection of volatile organic compounds (VOCs) is a common requirement in industry for which numerous methods are available. The electronic nose (e-nose) is an example. Rather than individual chemicals, the e-nose recognizes the ‘aroma fingerprint’ created by the collection of VOCs in samples, comparable to the human nose. We report on a novel application for gastrointestinal and metabolic medicine, and compare its results to mass spectrometry. Fermentation of undigested foods in the large bowel by its resident bacteria results in the creation of several chemicals including volatile gases that influence colonic and metabolic health. Using urine samples, preliminary results indicate the ability of the e-nose to distinguish between controls and those with inflammatory bowel disease or diabetes (separation rate of 97%). This emphasizes the different patterns of fermentation. Our term ‘fermentonomics’ describes the investigation and analysis of the fermentome by such non-invasive means. Such an approach has potentially wide application in medicine.

Item Type: Journal Article
Subjects: Q Science > QP Physiology
R Medicine > RC Internal medicine
Divisions: Faculty of Medicine > Warwick Medical School
Library of Congress Subject Headings (LCSH): Volatile organic compounds, Olfactometry, Inflammatory bowel diseases -- Diagnosis, Diabetes -- Diagnosis
Journal or Publication Title: Journal of Medical Engineering & Technology
Publisher: Taylor & Francis Ltd.
ISSN: 0309-1902
Official Date: February 2011
Dates:
DateEvent
February 2011Published
Volume: Vol.35
Number: No.2
Page Range: pp. 87-91
DOI: 10.3109/03091902.2010.539770
Status: Peer Reviewed
Publication Status: Published

Request changes or add full text files to a record

Repository staff actions (login required)

View Item View Item
twitter

Email us: wrap@warwick.ac.uk
Contact Details
About Us