Arasaradnam, Ramesh P., Ouaret, N., Joseph, M., Nwokolo, Chuka U., Wedlake, L., Andreyev, J., Bardhan, Karna Dev and Covington, James A., 1973- (2011) Radiation-induced gut damage : identifying 'at risk' patients with an 'electronic nose' (E-NOSE). In: Digestive Disease Week (DDW) 2011, Chicago, U.S.A., May 7-10, 2011. Published in: Gastroenterology, Vol.140 (No.5 Suppl.1). S184-S185.

Full text not available from this repository.

Abstract

Introduction Almost all patients undergoing radical pelvic radiotherapy develop bowel symptoms during treatment and half go on to develop chronic bowel symptoms. Acute histological damage, due to the radiation, is at its worst at 2 weeks and then improves; subsequent chronic damage then is sustained over many years. We investigated if changes in gastrointestinal symptoms during radiotherapy correlated with alterations in colonic microbial balance, reflected by changes in the gases released when undigested fibre is fermented. Two hypotheses were investigated in this pilot study: (1) Irradiation alter the microbial flora, reflected by changes in the fermentation profile. (2) An individual's susceptibility to damage may be recognised by their ‘fermentation signature'.

Item Type:	Conference Item (Paper)
Subjects:	R Medicine > R Medicine (General)
Divisions:	Faculty of Science > Engineering
Journal or Publication Title:	Gastroenterology
Publisher:	W.B. Saunders Co.
ISSN:	0016-5085
Date:	May 2011
Volume:	Vol.140
Number:	No.5 Suppl.1
Page Range:	S184-S185
Identification Number:	10.1136/gut.2011.239301.227
Status:	Peer Reviewed
Publication Status:	Published
Access rights to Published version:	Restricted or Subscription Access
Conference Paper Type:	Paper
Title of Event:	Digestive Disease Week (DDW) 2011
Type of Event:	Conference
Location of Event:	Chicago, U.S.A.
Date(s) of Event:	May 7-10, 2011
URI:	http://wrap.warwick.ac.uk/id/eprint/45939

Data sourced from Thomson Reuters' Web of Knowledge

Request changes to a record

Actions (login required)

View Item