Kaltenthaler, E. (Eva), Brazier, John, De Nigris, E., Tumur, I., Ferriter, Michael, Beverley, C., Parry, G., Rooney, G. and Sutcliffe, Paul A.. (2006) Computerised cognitive behaviour therapy for depression and anxiety update : a systematic review and economic evaluation. Health Technology Assessment, Vol.10 (No.33). pp. 1-186. ISSN 1366-5278

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Abstract

Objectives: To evaluate computerised cognitive behaviour therapy (CCBT) for the treatment of anxiety, depression, phobias, panic and obsessive–compulsive behaviour (OCD). The software packages to be considered include Beating the Blues (BtB), Overcoming Depression: a five areas approach, FearFighter (FF), Cope and BT Steps. Other packages or programmes incorporating CCBT were also considered. Data sources: Electronic databases from 1966 to March 2004. Evidence submitted by sponsors for CCBT products. Review methods: A systematic review was a review of the literature and the evidence submitted by sponsors for each of the products. A series of cost-effectiveness models was developed and run by the project team for the five CCBT products across the three mental health conditions. Results: Twenty studies were identified in the clinical effectiveness review. The analysis of these results showed some evidence that CCBT is as effective as therapist-led cognitive behaviour therapy (TCBT) for the treatment of depression/anxiety and phobia/panic and is more effective than treatment as usual (TAU) in the treatment of depression/anxiety. CCBT also appears to reduce therapist time compared with TCBT. When reviewing cost-effectiveness studies, only one published economic evaluation of CCBT was found. This was an economic evaluation of the depression software BtB alongside a randomised controlled trial (RCT), which found that BtB was cost-effective against TAU in terms of cost per quality-adjusted life-year (QALY) (less than £2000), however it contained weaknesses that were then addressed in the cost-effectiveness model developed for the study. The results of the model for the depression software packages in terms of incremental cost per QALY compared with TAU and the chance of being cost-effective at £30,000 per QALY were for BtB £1801 and 86.8%, for Cope £7139 and 62.6% and for Overcoming Depression £5391 and 54.4%. The strength of the BtB software being that it has been evaluated in the context of an RCT with a control group. The subgroup analysis found no differences across the severity groupings. For phobia/panic software, the model showed an incremental cost per QALY of FF over relaxation was £2380. Its position compared with TCBT is less clear. When modelling OCD packages, using the practice-level licence cost meant that BT Steps was dominated by TCBT, which had significantly better outcomes and was cheaper. However, the cheaper PCT licence resulted in the incremental cost-effectiveness of BT Steps over relaxation being £15,581 and TCBT over BT Steps being £22,484. Conclusions: The study findings are subject to substantial uncertainties around the organisational level for purchasing these products and the likely throughput. This is in addition to concerns with the quality of evidence on response to therapy, longer term outcomes and quality of life. The position of CCBT within a stepped care programme needs to be identified, as well as its relationship to other efforts to increase access to CBT and psychological therapies. Research is needed to compare CCBT with other therapies that reduce therapist time, in particular bibliotherapy and to explore the use of CCBT via the Internet. Independent research is needed, particularly RCTs, that examine areas such as patient preference and therapist involvement within primary care.

Item Type:	Journal Article
Subjects:	R Medicine > RC Internal medicine
Divisions:	Faculty of Medicine > Warwick Medical School
Library of Congress Subject Headings (LCSH):	Neuroses -- Treatment -- Cost effectiveness, Cognitive therapy, Clinical medicine -- Computer programs
Journal or Publication Title:	Health Technology Assessment
Publisher:	NIHR Health Technology Assessment programme
ISSN:	1366-5278
Date:	September 2006
Volume:	Vol.10
Number:	No.33
Page Range:	pp. 1-186
Identification Number:	10.3310/hta10330
Status:	Peer Reviewed
Publication Status:	Published
Access rights to Published version:	Open Access
Funder:	NIHR Health Technology Assessment Programme (Great Britain)
References:	1. Department of Health. National Service Framework for Mental Health: modern standards and service models. Health Service circular. Series No. HSC 1999/223: LAC (99) 34. London: Department of Health; 1999. 2. Department of Health. Treatment choice in psychological therapies and counselling. Evidence Based Clinical Practice Guideline. London: Department of Health; 2001. 3. Bebbington PE, Meltzer H, Brugha TS, Farrell M, Jenkins R, Ceresa C, et al. Unequal access and unmet need: neurotic disorders and the use of primary care services. Psychol Med 2000;30;1359–67. 4. Hirschfeld RMA, Keller MB, Panico S, Arons BS, Barlow D, Davidoff F, et al. The National Depressive and Manic-Depressive Association consensus statement on the undertreatment of depression. JAMA 1997;277(4):333–40. 5. NHS Centre for Reviews and Dissemination, University of York. Improving the recognition and management of depression in primary care. Effective Health Care 2002;7:1–11. 6. Marks J, Goldberg D, Hiller V. Determinants of the ability of general practitioners to detect psychiatric illness. Psychol Med 1979;9:337–53. 7. Mulsant BH, Ganguli M. Epidemiology and diagnosis of depression in late life [review]. Journal of Clinical Psychiatry 1999;60(Suppl 20):9–15. 8. Lepine JP. Epidemiology, burden, and disability in depression and anxiety. J Clin Psychiatry 2001; 62(Suppl 13):4–10. 9. Smith B, Caputi P. Cognitive interference in computer anxiety. Behaviour and Information Technology 2001;20:265–73. 10. American Psychiatric Association. Diagnostic and statistical manual of mental disorders. 4th ed. (DSMIV). Washington, DC: APA; 1994. 11. The ICD-10 classification of mental and behavioural disorders: clinical descriptions and diagnostic guidelines. Geneva: World Health Organization; 1992. 12. Kennedy SH, Lam RW, Morris B. Clinical guidelines for depressive disorders: summary of recommendations relevant to family physicians. Can Fam Physician 2003;49:489–91. 13. Bebbington PE, Dunn G, Jenkins R, Lewis G, Brugha T, Farrell M, et al. The influence of age and sex on the prevalence of depressive conditions: report from the National Survey of Psychiatric Morbidity. Psychol Med 1998;28:9–19. 14. Clinical Standards Advisory Group (CSAG). Depression. London: HMSO; 1999. 15. Beekman ATF, Geerlings SW, Deeg DJH, Smit JH, Schoevers RS, De Beurs E, et al. The natural history of late-life depression – a 6-year prospective study in the community. Arch Gen Psychiatry 2002;59:605–11. 16. Freudenstein U, Jagger C, Arthur A, Donner- Banzhoff, N. Treatments for late life depression in primary care – a systematic review. Fam Pract 2001;18:321–7. 17. Fletcher J, Bower P, Richards D. Enhanced services specification for depression under the new GP contract. A commissioning guidebook. 2004. 18. Regier DA, Rae DS, Narrow WE, Kaelber CT, Schatzberg AF. Prevalence of anxiety disorders and their comorbidity with mood and addictive disorders. Br J Psychiatry Suppl 1998;173(S34):24–8. 19. Weiller E, Bisserbe JC, Maier W, Lecrubier Y. Prevalence and recognition of anxiety syndromes in five European primary care settings. A report from the WHO study on Psychological Problems in General Health Care. Br J Psychiatry Suppl 1998;173(S34):18–23. 20. Meltzer H, Gill B, Petticrew M, Hinds K. OPCS Surveys of Psychiatric Morbidity in Great Britain. Report 2: Physical complaints, service use and treatment of adults with psychiatric disorders. London: HMSO; 1995. 21. Pigott TA. Gender differences in the epidemiology and treatment of anxiety disorders [review]. J Clin Psychiatry 1999;60(Suppl 18):4–15. 22. Birchall H, Brandon S, Taub N. Panic in a general practice population: prevalence, psychiatric comorbidity and associated disability. Soc Psychiatry Psychiatri Epidemiol 2000;35:235–41. 23. Klerman GL, Weissman MM, Ovellette R, Like J. Panic attacks in the community: social morbidity and health care utilization. JAMA 1991;265: 742–6. 24. Curtis GC, Magee WJ, Eaton WW, Wittchen HU, Kessler RC. Specific fears and phobias. Epidemiology and classification. Br J Psychiatry 1998;173:212–17. 25. Stein MB, Kean YM. Disability and quality of life in social phobia: epidemiologic findings. Am J Psychiatry 2000;157:1606–13. 26. Lang AJ, Stein MB. Social phobia: prevalence and diagnostic threshold [review]. J Clin Psychiatry 2001;62(Suppl 1):5–10. 27. Lopez-Ibor JJ, Lopez-Ibor MI. Research on obsessive–compulsive disorder. Current Opinion in Psychiatry 2003;16:S85–91. 28. Nymberg JH, Van Noppen B. Obsessive–compulsive disorder: a concealed diagnosis [review]. Am Fam Physician 1994;49:1129–37. 29. Karno M, Golding JM, Sorenson SB, Burnam MA. The epidemiology of obsessive–compulsive disorder in five US communities. Arch Gen Psychiatry 1988;45:1094–9. 30. Oakley-Brown M. The epidemiology of anxiety disorders. International Journal of Psychiatry 1991; 3:243–52. 31. Eisen JL, Goodman WK, Keller MB, Warshaw MG, DeMarco LM, Luce DD, et al. Patterns of remission and relapse in obsessive-compulsive disorder: a 2- year prospective study. J Clin Psychiatry 1999;60:346–51. 32. James IA, Blackburn IM. Cognitive therapy with obsessive-compulsive disorder [see comment] [review]. Br J Psychiatry 1995;166:444–50. 33. Kobak KA, Greist JH, Jefferson JW, Katzelnick DJ, Henk HJ. Behavioral versus pharmacological treatments of obsessive compulsive disorder: a meta-analysis. Psychopharmacology 1998;136:205–16. 34. Abramowitz JS. Effectiveness of psychological and pharmacological treatments for obsessive–compulsive disorder: a quantitative review. J Consult Clin Psychol 1997;65:44–52. 35. Salkovskis AM, Kirk J. Obsessive–compulsive disorder. New York: Oxford University Press; 1997. pp. 179–208. 36. British National Formulary 36. London: British Medical Association and Royal Pharmaceutical Society of Great Britain; 1998. 37. Mental health – anxiety. Health Evidence Bulletins – Wales. National Institute of Mental Health, 1998. http://hebw.uwcm.ac.uk/mental/chapter8.html 38. Brunello N, den Boer JA, Judd LL, Kasper S, Kelsey JE, Lader M, et al. Social phobia: diagnosis and epidemiology, neurobiology and pharmacology, comorbidity and treatment. J Affect Disord 2000;60:61–74. 39. NIMH(E). Organising and delivering psychological therapies. London: Department of Health; 2004. 40. House of Commons Select Committee on Health. Fourth Report. Provision of NHS mental health services; London: Houses of Commons, 2000. http://www.publications.parliment.uk/pa/cm199900 /cmselect/cmhealth/373/37310.htm. 41. National Institute For Clinical Excellence and National Collaborating Centre for Mental Health. Depression: management of depression in primary and secondary care. London: National Institute for Clinical Excellence, 2004. http://www.nice.org.uk/cg023NICEguideline. 42. National Institute For Clinical Excellence. Clinical guidelines for the management of panic disorder and generalised anxiety disorder. London: National Institute for Clinical Excellence, 2004. http://www.nice.org.uk/page.aspx?0=235400. 43. Heimberg RG. Current status of psychotherapeutic interventions for social phobia. J Clin Psychiatry 2001;62(Suppl 1):36–42. 44. Lovell K, Richards D. Multiple Access Points and Levels of Entry (MAPLE): ensuring choice, accessibility and equity for CBT services. Behavioural and Cognitive Psychotherapy 2000; 28:379–91. 45. King M, Sibbald B, Ward E, Bower P, Lloyd M, Gabbay M, et al. Randomised controlled trial of non-directive counselling, cognitive-behaviour therapy and usual general practitioner care in the management of depression as well as mixed anxiety and depression in primary care. Health Technol Assess 2000;4(19). 46. Barlow DH, Gorman JM, Shear K, Woods SW. Cognitive-behavioral therapy, imipramine or their combination for panic disorder. JAMA 2001; 283:2529–36. 47. Churchill R, Hunot V, Corney R, Knapp M, McGuire H, Tylee A, et al. A systematic review of controlled trials of the effectiveness and costeffectiveness of brief psychological treatments for depression. Health Technol Assess 2001;5(35). 48. Gould RA. A meta-analysis of treatment outcome for panic disorder. Clin Psychol Rev 1995;15:819–44. 49. Durham RC, Murphy T, Allan T, Richard K. Cognitive therapy, analytic psychotherapy and anxiety management training for generalised anxiety disorder. Br J Psychiatry 1994;165:315–23. 50. Sharp DM, Power KG, Swanson V. Reducing therapist contact in cognitive behaviour therapy for panic disorder and agoraphobia in primary care: global measures of outcome in a randomised controlled trial. Br J Gen Pract 2000;50:963–8. 51. Power KG, Sharp DM, Swanson V, Simpson RJ. Therapist contact in cognitive behaviour therapy for panic disorder and agoraphobia in primary care. Clinical Psychology and Psychotherapy 2000; 7:37–46. 52. Byford S, Bower P. Cost-effectiveness of cognitivebehavioral therapy for depression: current evidence and future research priorities. Expert Review of Pharmacoeconomics and Outcomes Research 2002;2:457–65. 53. Newman MG, Erickson T, Przeworski A, Dzus E. Self-help and minimal-contact therapies for anxiety disorders: is human contact necessary for therapeutic efficacy? J Clin Psychol 2003;59:251–74. 54. Richards A, Barkham M, Cahill J, Richards D, Williams C, Heywood P. PHASE: a randomised, controlled trial of supervised self-help cognitive behavioural therapy in primary care. Br J Gen Pract 2003;53:764–70. 55. Dowrick C, Dunn G, Ayuso-Mateos JL, Dalgard OS, Page H, Lehtinen V, et al. Problem solving treatment and group psychoeducation for depression: multicentre randomised controlled trial. Outcomes of Depression International Network (ODIN) Group. BMJ 2000;321:1450–4. 56. Dowrick C, Casey P, Dalgard O. Outcomes of Depression International Network (ODIN). Br J Psychiatry 1998;172:359–63. 57. Williams C. Use of written cognitive-behavioural therapy self-help materials to treat depression. Advances in Psychiatric Treatment 2001;7:233–40. 58. Bower P, Richards D, Lovell K. The clinical and cost-effectiveness of self-help treatments for anxiety and depressive disorders in primary care: a systematic review. Br J Gen Pract 2001;51:838–45. 59. Cuijpers P. Bibliotherapy in unipolar depression: a meta-analysis. J Behav Ther Exp Psychiatry 1997;28:139–47. 60. McKendree-Smith NL, Floyd M, Scogin FR. Selfadministered treatments for depression: a review. J Clin Psychol 2003;59:275–88. 61. Scogin FR, Bynum J, Stephens G. Efficacy of selfadministered treatment programs: meta-analytic review. Professional Psychology: Research and Practice 1990;21:42–7. 62. Marrs RW. A meta-analysis of bibliotherapy studies. Am J Community Psychol 1995;23:843–70. 63. Scogin F, Bynum J, Stephens G, Calhoon S. Efficacy of self-administered programs: metaanalytic review. Professional Psychology: Research and Practice 1990;21:42–7. 64. Gould RA, Clum GA. A meta-analysis of self-help treatment approaches. Clin Psychol Rev 1993; 13:169–86. 65. Mead N, Macdonald W, Bower P, Lovell K, Richards D, Roberts C, et al. The clinical effectiveness of guided self-help versus waiting list control in the management of anxiety and depression: a randomised controlled trial. Psychol Med 2005;35:1633–43. 66. Willemse GWM, Smit F, Cuijpers P, Tiemens BG. Minimal-contact psychotherapy for sub-threshold depression in primary care. Br J Psychiatry 2004; 185:416–21. 67. Keeley H, Williams C, Shapiro DA. A United Kingdom survey of accredited Cognitive Behaviour Therapists’ attitudes towards and use of structured self-help materials. Behavioural and Cognitive Psychotherapy 2002;30:191–201. 68. Bower P, Gilbody S. ‘Getting the biggest bang for your (limited) buck’: issues in the implementation and evaluation of stepped care in psychological therapies in the NHS. 2004. 69. Newman MG, Consoli A, Taylor CB Computers in assessment and cognitive behavioral treatment of clinical disorders: anxiety as a case in point. Behavior Therapy 1997;28:211–35. 70. Greist JH. Computer interviews for depression management. J Clin Psychiatry 1998;59(Suppl 16): 20–4. 71. Finfgeld DL. Computer-assisted therapy: harbinger of the 21st century? Arch Psychiatr Nurs 1999;13:303–10. 72. Greist JH, Osgood-Hynes DJ, Baer L, Marks IM. Technology-based advances in the management of depression: Focus on the COPE™ program. Disease Management and Health Outcomes 2000;7:193–200. 73. Ghosh A, Greist JH. Computer treatment in psychiatry. Psychiatric Annals 1988;18:246–50. 74. Wright JH, Wright AS. Computer-assisted psychotherapy. Journal of Psychotherapy Practice and Research 1997;6:315–29. 75. Information Policy Unit. Building the information core. Protecting and using confidential patient information. A strategy for the NHS. London: Department of Health; 2001. 76. Dolezal-Wood S, Belar CD, Snibbe JA. A comparison of computer-assisted psychotherapy and cognitive-behavioral therapy in groups. Journal of Clinical Psychology in Medical Settings 1998;5:103–15. 77. Taylor CB, Luce KH. Computer- and Internetbased psychotherapy interventions. Current Directions in Psychological Science 2003;12:18–22. 78. Andrews G, Erskine A. Reducing the burden of anxiety and depressive disorders: the role of computerized clinician assistance. Current Opinion in Psychiatry 2003;16:41–4. 79. Whtifield G, Williams C. If the evidence is so good – why doesn’t anyone use them? A national survey of the use of computerised cognitive behaviour therapy. 2004. 80. National Institute for Clinical Excellence. Guidance on the use of computerised cognitive behavioural therapy for anxiety and depression. London: NICE; 2002. 81. Critical Appraisal Skills Programme (CASP). Checklist for appraising RCTs. 2004. http://www.phry.nhs.uk/casp/rcts.htm 82. Downs SH, Black N. The feasibility of creating a checklist for the assessment of the methodological quality of both randomised and non-randomised studies of health care interventions. J Epidemiol Community Health 1998;52:377–84. 83. Cohen J. Statistical power analysis for the behavioural sciences. 2nd ed. New Jersey: Lawrence Earlbaum, 1988. 84. Cavanagh K. Beating the Blues. Ultrasis submission to NICE; 2004. 85. Kenwright M, Liness S, Marks I. Reducing demands on clinicians by offering computer-aided self-help for phobia/panic. Feasibility study. Br J Psychiatry 2001;179:456–9. 86. Kenwright M, Marks IM, Gega L, Mataix-Cols D. Computer-aided self-help for phobia/panic via internet at home: a pilot study. Br J Psychiatry 2004;184:448–9. 87. Proudfoot J, Ryden C, Everitt B, Shapiro D, Goldberg D, Mann A, et al. Clinical efficacy of computerised cognitive-behavioural therapy for anxiety and depression in primary care: randomised controlled trial. Br J Psychiatry 2004; 185:46–54. 88. Marks IM, Kenwright M, McDonough M, Whittaker M, Mataix-Cols D. Saving clinicians’ time by delegating routine aspects of therapy to a computer: a RCT in phobia/panic disorder. Psychol Med 2004;34:9–18. 89. Marks IM, Mataix-Cols D, Kenwright M, Cameron R, Hirsch S, Gega L. Pragmatic evaluation of computer-aided self-help for anxiety and depression. Br J Psychiatry 2003;183:57–65. 90. Schneider A, Mataix-Cols D, Marks IM, Bachofen M. Internet-guided self-help with or without exposure therapy for phobia/panic disorder: a randomised controlled trial. Psychother Psychosoma 2005;74:154–64. 91. Osgood-Hynes DJ, Greist JH, Marks IM, Baer L, Heneman SW, Wenzel KW, et al. Self-administered psychotherapy for depression using a telephoneaccessed computer system plus booklets: an open US–UK study. J Clin Psychiatry 1998;59:358–65. 92. Carlbring P, Westling BE, Ljungstrand P, Ekselius L, Andersson G. Treatment of panic disorder via the Internet: a randomized trial of a self-help program. Behavior Therapy 2001; 32:751–64. 93. Whitfield G, Hinshelwood R, Pashely A, Campsie L, Williams C. The impact of a novel computerised CBT CD Rom (Overcoming Depression) offered to patients referred to clinical psychology. Unpublished Media Innovations Submission to NICE; 2004. 94. Carlbring P, Ekselius L, Andersson G. Treatment of panic disorder via the Internet: a randomized trial of CBT vs. applied relaxation. J Behav Ther Exp Psychiatry 2003;34:129–40. 95. Christensen H, Griffiths KM, Jorm AF. Delivering interventions for depression by using the internet: randomised controlled trial. BMJ 2004;328:265–8. 96. Carlbring P, Nilsson-Ihrfelt E, Waara J, Kollenstam C, Buhrman M, Kaldo V, et al. Treatment of panic disorder: live therapy vs. self-help via the internet. 2004. 97. Clarke G, Reid E, Eubanks D, O’Connor E, DeBar LL, Kelleher C, et al. Overcoming Depression on the Internet (ODIN): a randomized controlled trial of an Internet depression skills intervention program. J Med Internet Res 2002; 4:E14. 98. Fraser J, Kirkby KC, Daniels B, Gilroy L, Montgomery IM. Three versus six sessions of Computer-Aided Vicarious Exposure treatment for spider phobia. Behaviour Change 2001;18:213–23. 99. Gilroy LJ, Kirkby KC, Daniels BA, Menzies RG, Montgomery IM. Long-term follow-up of Computer-Aided Vicarious Exposure versus live graded exposure in the treatment of spider phobia. Behavior Therapy 2003;34:65–76. 100. Yates F. Part Two: Evaluation of the Balance computer intervention. 1996. 101. Heading K, Kirkby KC, Martin F, Daniels BA, Gilroy LJ, Menzies RG. Controlled comparison of single-session treatments for spider phobia: live graded exposure alone versus Computer-Aided Vicarious Exposure. Behaviour Change 2001; 18:103–13. 102. Proudfoot J, Goldberg D, Mann A, Everitt B, Marks I, Gray JA. Computerized, interactive, multimedia cognitive-behavioural program for anxiety and depression in general practice [see comment]. Psychol Med 2003;33:217–27. 103. Proudfoot J, Swain S, Widmer S, Watkins E, Goldberg D, Marks I, et al. The development and beta-test of a computer-therapy program for anxiety and depression: hurdles and lessons. Computers in Human Behavior 2003;19:277–89. 104. Grime PR. An open, randomised study, to compare the effects of a computerised cognitive behavioural therapy programme (‘Beating the Blues’) plus conventional care, vs conventional care alone, on absence from work due to anxiety, depression or stress. An attempt to evaluate a workplace intervention for stress. London: Faculty of Occupational Medicine, Royal College of Physicians; 2001. 105. Shaw SC, Marks IM, Toole S. Lessons from pilot tests of computer self-help for agora/claustrophobia and panic. MD Computing 1999;16:44–8. 106. Jadad AJ, Moore A, Carroll D, Jenkinson C, Reynolds DJM, Gavaghan DJ, et al. Assessing the quality of reports of randomized clinical trials: is blinding necessary? Control Clin Trials 1996;17:1–12. 107. Gilroy LJ, Kirkby KC, Daniels BA, Menzies RG, Montgomery IM. Controlled comparison of computer-aided vicarious exposure versus live exposure in the treatment of spider phobia. Behavior Therapy 2000;31:733–44. 108. Ghosh A, Marks IM, Carr AC. Therapist contact and outcome of self-exposure treatment for phobias. Br J Psychiatry 1988;152:234–8. 109. Jones RB, Kamarzaman Z, Naven LM, Morton WR, Marriott C, Craig N, et al. Cognitive behavioural computer therapy for anxiety: difficulties in carrying out a randomised trial and lessons learned. 2001. 110. Graham C, Franses A, Kenwright M, Marks I. Psychotherapy by computer: a postal survey of responders to a teletext article. Psychiatric Bulletin 2000;24:331–2. 111. Keaverny E, Blackburn K. A survey of East Primary Care Trust general practitioners’ views, about their use of ‘Beating the Blues’ computer based serviceuser treatment program. 2004. 112. Coxall L, Blackburn K. The utility of the Beating the Blues – computer based cognitive therapy program in secondary care. 2004. 113. Gruber K, Moran PJ, Roth WT, Taylor CB. Computer-assisted cognitive behavioral group therapy for social phobia. Behavior Therapy 2001; 32:155–65. 114. Kenardy JA, Dow MGT, Johnston DW, Newman MG, Thomson A, Taylor CB. A comparison of delivery methods of cognitive-behavioral therapy for panic disorder: an international multicenter trial. J Consult Clin Psychol 2003;71:1068–75. 115. Greist JH, Marks IM, Baer L, Kobak KA, Wenzel KW, Hirsch MJ, et al. Behavior therapy for obsessive-compulsive disorder guided by a computer or by a clinician compared with relaxation as a control. J Clin Psychiatry 2002; 63:138–45. 116. Kenwright M, Marks I, Graham C. Brief scheduled phone support from a clinician to enhance computer-aided self-help for obsessive–compulsive disorder: randomised controlled trial. J Clin Psychol 2005;61:1499–508. 117. Greist JH, Marks IM, Baer L, Parkin JR, Manzo PA, Mantle JM, et al. Self-treatment for obsessive compulsive disorder using a manual and a computerized telephone interview: a US–UK study. MD Computing 1998;15:149–57. 118. Bachofen M, Nakagawa A, Marks IM, Park JM, Greist JH, Baer L, et al. Home self-assessment and self-treatment of obsessive–compulsive disorder using a manual and a computer-conducted telephone interview: replication of a UK–US study. J Clin Psychiatry 1999;60:545–9. 119. Nakagawa A, Marks IM, Park JM, Bachofen M, Baer L, Dottl SL, et al. Self-treatment of obsessive–compulsive disorder guided by manual and computer-conducted telephone interview. J Telemed Telecare 2000;6:22–6. 120. McCrone P, Knapp M, Proudfoot J, Ryden C, Cavanagh K, Shapiro DA, et al. Cost-effectiveness of computerised cognitive-behavioural therapy for anxiety and depression in primary care: randomised controlled trial. Br J Psychiatry 2004;185:55–62. 121. van den Berg S, Shapiro DA, Bickerstaffe D, Cavanagh K. Computerized cognitive-behaviour therapy for anxiety and depression: a practical solution to the shortage of trained therapists. Journal of Psychiatric and Mental Health Nursing 2004;13:173–9. 122. Fox E, Acton T, Wilding B, Corcoran S. Service development report: an assistant psychologist’s perspective on the use of computerised CBT in a GP practice in Barnet. Quality in Primary Care 2004;12:161–5. 123. Cavanagh K, Shapiro DA. Computer treatment for common mental health problems. J Clin Psychol 2004;60:239–51. 124. Kaltenthaler E, Shackley P, Stevens K, Beverley C, Parry G, Chilcott J. A systematic review and economic evaluation of computerised cognitive behaviour therapy for depression and anxiety. Health Technol Assess 2002;6(22). 125. Proudfoot JG. Computer-based treatment for anxiety and depression: is it feasible? Is it effective? Neurosci Biobehav Rev 2004;28:353–63. 126. ST Solutions Ltd. BT Steps. Submission to NICE; 2004. 127. Marks IM, Baer L, Greist JH, Park JM, Bachofen M, Nakagawa A, et al. Home self-assessment of obsessive–compulsive disorder. Use of a manual and a computer-conducted telephone interview: two UK-US studies. Br J Psychiatry 1998;172:406–12. 128. Lave JR, Frank RG, Schulberg HC, Kamlet MS. Cost-effectiveness of treatments for major depression in primary care practice. Arch Gen Psychiatry 1998;55:645–51. 129. Singleton N, Bumpstead R, O’Brien M, Lee A, Meltzer H. Psychiatric morbidity among adults living in private households, 2000: summary report. London: Office of National Statistics; 2000. 130. Goldberg D, Huxley P. Mental illnesses in the community: the path to psychiatric care. London: Tavistock; 1980. 131. Beck AT, Steer RA, Garbin MG. Psychometric properties of the BDI: 25 years of evaluation. Clin Psychol Rev 1988;8:77–100. 132. Thase ME, Simons AD, McGeary J, Cahalane JF, Hughes C, Harden T, et al. Relapse after cognitive behavior therapy of depression: potential implications for longer courses of treatment. Am J Psychiatry 1992;149:1046–52. 133. Kind P, Dolan P, Gudex C, Williams A. Variations in population health status: results from a UK national questionnaire survey. BMJ 1998; 316:736–41. 134. Marks I, Mathews AM. Brief standard self-rating for phobic patients. Behav Res Ther 1978; 17:263–7. 135. Liebowitz MR, Heimberg RG, Schneider FR, Hope DA, Davis S, Holt CS, et al. Cognitivebehavioural group therapy versus phenelzine in social phobia: long term outcome. Depress Anxiety 1999;10:89–98. 136. Netten A, Curtis L. Unit costs of health and social care. University of Kent, Canterbury: PSSRU; 2003. 137. Alonso J, Angermeyer MC, Lepine JP. The European Study of the Epidemiology of Mental Disorders (ESEMeD) project: an epidemiological basis for informing mental health policies in Europe. Acta Psychiatr Scand 2004;109(Suppl 420):5–7. 138. Brazier JE, Roberts J, Deverill M. The estimation of a preference based simple index for health from the SF-36. Journal of Health Economics 2002;21:271–92. 139. Goodman WK, Price LH. Rating scales for obsessive–compulsive disorder. St Louis, MO: Mosby; 1998. pp. 97–117. 140. Luborsky L, Diguer L, Seligman DA, Rosenthal R, Krause ED, Johnson S. The researcher’s own therapy allegiances: a ‘wild card’ in comparisons of treatment efficacy. Clinical Psychology – Science and Practice 1999;6:95–106. 141. Hetherton J, Matheson A, Robson M. Recruitment by GPs during consultations in a primary care randomized controlled trial comparing computerized psychological therapy with clinical psychology and routine GP care: problems and possible solutions. Primary Health Care Research and Development 2004;5:5–10. 142. Munro J, Nicholl J, O’Cathain A, Knowles E, Morgan A. Evaluation of NHS Direct first wave sites. Final report of the phase 1 research. Sheffield: Medical Care Research Unit, ScHARR, University of Sheffield; 2001. 143. Hatziandreu EJ, Brown RE, Revicki DA, Turner R, Martindale J, Levine S, et al. Cost utility of maintenance treatment of recurrent depression with sertraline versus episodic treatment with dothiepin. Pharmacoeconomics 1994;5:249–68. 144. Kamlet MS, Paul N, Greenhouse J, Kupfer D, Frank E, Wade M. Cost utility analysis of maintenance treatment for recurrent depression. Control Clin Trials 1995;16:17–40. 145. Revicki MW. Patient-assigned health state utilities for depression-related outcomes: differences by depression severity and antidepressant medications. J Affect Disord 1998;48:25–36. 146. Lenert LA, Sherbourne CD, Sugar C, Wells KB. Estimation of utilities for the effects of depression from the SF-12. Med Care 2000;38:763–70. 147. Revicki DA, Brown RE, Palmer W. Modeling the cost effectiveness of antidepressant treatment in primary care. Pharmacoeconomics 1995;8: 524–40. 148. Revicki DA, Brown RE, Keller MB. Costeffectiveness of newer antidepressants compared with tricyclic antidepressants in managed care settings. J Clin Psychiatry 1997;58:47–58. 149. Schaffer A, Levitt AJ, Hershkop SK, Oh P, MacDonald C, Lanctot K. Utility scores of symptom profiles in major depression. Psychiatry Res 2002;110:189–97. 150. Wells K, Sherbourne CD. Functioning and utility for current health of patients with depression or chronic medical conditions in managed, primary care practices. Arch Gen Psychiatry 1999; 56:897–904. 151. Bennett KJ, Torrance GW. Development and testing of a utility measure for major, unipolar depression. Qual Life Res 2000. 152. Simon NM, Otto MW, Korbly NB, Peters PM, Nicolaou DC, Pollack MH. Quality of life in social anxiety disorder compared with panic disorder and the general population. Psychiatr Serv 2002; 53:714–8. 153. Alonso J, Angermeyer MC, Bernert S, Bruffaerts R, Brugha TS, Bryson H, et al. Disability and quality of life impact of mental disorders in Europe: results from the European Study of the Epidemiology of Mental Disorders (ESEMeD) project. Acta Psychiatr Scand 2004; 109(Suppl 420):38–46. 154. Koran LM. Quality of life for patients with obsessive compulsive disorder. Am J Psychiatry 1996;153:783–8. 155. Pyne JM, Bullock D, Kaplan RM, Smith TL, Gillin JC, Golshan S, et al. Health-related qualityof- life measure enhances acute treatment response prediction in depressed inpatients. J Clin Psychiatry 2001;62:261–8. 156. Gega L, Marks I. Computer-aided CBT self-help for anxiety and depressive disorders: experiences of a London clinic and future directions. J Clin Psychol 2004;60:147–57.
URI:	http://wrap.warwick.ac.uk/id/eprint/46334

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