Severe thiamine deficiency complicated by weight loss protects against renal ischaemia-reperfusion injury in rats
Klooster, A., Larkin, J. R., Adaikalakoteswari, A., Gans, R. O. B., van Goor, H., Thornalley, Paul J., Rabbani, N., Navis, G., Leuvenink, H. G. D. and Bakker, S. J. L. (2009) Severe thiamine deficiency complicated by weight loss protects against renal ischaemia-reperfusion injury in rats. NDT Plus, Vol.2 (No.2). pp. 182-183. ISSN 1753-0784Full text not available from this repository.
Official URL: http://dx.doi.org/10.1093/ndtplus/sfn194
Injury due to reperfusion after prior ischaemia (IRI) is an important cause of delayed graft function after renal transplantation . Studies in dogs and rats suggest that thiamine is protective against IRI in heart and brain [2–4]. It has been argued that many organs, including kidneys are deficient in thiamine at the moment of transplantation . We aimed to investigate the effect of severe tissue thiamine deficiency on ischaemia-reperfusion injury in rat kidneys.
|Item Type:||Journal Item|
|Subjects:||R Medicine > R Medicine (General)|
|Divisions:||Faculty of Medicine > Warwick Medical School > Metabolic and Vascular Health
Faculty of Medicine > Warwick Medical School
|Journal or Publication Title:||NDT Plus|
|Publisher:||Oxford University Press|
|Page Range:||pp. 182-183|
|Access rights to Published version:||Restricted or Subscription Access|
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