Klooster, A., Larkin, J. R., Antonysunil, Adaikalakoteswari, Gans, R. O. B., van Goor, H., Thornalley, Paul J., Rabbani, Naila, Navis, G., Leuvenink, H. G. D. and Bakker, S. J. L. (2009) Severe thiamine deficiency complicated by weight loss protects against renal ischaemia-reperfusion injury in rats. NDT Plus, Vol.2 (No.2). pp. 182-183. doi:10.1093/ndtplus/sfn194

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Abstract

Injury due to reperfusion after prior ischaemia (IRI) is an important cause of delayed graft function after renal transplantation [1]. Studies in dogs and rats suggest that thiamine is protective against IRI in heart and brain [2–4]. It has been argued that many organs, including kidneys are deficient in thiamine at the moment of transplantation [4]. We aimed to investigate the effect of severe tissue thiamine deficiency on ischaemia-reperfusion injury in rat kidneys.

Item Type:	Journal Item
Subjects:	R Medicine > R Medicine (General)
Divisions:	Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Biomedical Sciences > Translational & Experimental Medicine > Metabolic and Vascular Health (- until July 2016) Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School
Journal or Publication Title:	NDT Plus
Publisher:	Oxford University Press
ISSN:	1753-0784
Official Date:	April 2009
Dates:	Date Event April 2009 Published
Volume:	Vol.2
Number:	No.2
Page Range:	pp. 182-183
DOI:	10.1093/ndtplus/sfn194
Status:	Peer Reviewed
Publication Status:	Published
Access rights to Published version:	Restricted or Subscription Access

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