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Simon's minimax and optimal and Jung's admissible two-stage designs with or without curtailment
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Kunz, Cornelia and Kieser, M.. (2011) Simon's minimax and optimal and Jung's admissible two-stage designs with or without curtailment. Stata Journal, Vol.11 (No.2). pp. 240-254. ISSN 1536-867X
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Official URL: http://www.stata-press.com/journals/
Abstract
This article describes a new Stata command called simontwostage, which calculates the critical values and sample sizes for two-stage designs for phase II oncology trials. Options are provided to determine the minimax and optimal designs proposed by Simon (1989, Controlled Clinical Trials 10: 1–10) and admissible designs described by Jung et al. (2004, Statistics in Medicine 23: 561–569). Furthermore, nonstochastic and stochastic curtailment rules can be implemented in both stages of the trial, and the properties of the curtailed designs can be examined.
| Item Type: | Journal Article |
|---|---|
| Subjects: | R Medicine > R Medicine (General) |
| Divisions: | Faculty of Medicine > Warwick Medical School > Health Sciences Faculty of Medicine > Warwick Medical School |
| Journal or Publication Title: | Stata Journal |
| Publisher: | Stata Press |
| ISSN: | 1536-867X |
| Official Date: | 2011 |
| Volume: | Vol.11 |
| Number: | No.2 |
| Page Range: | pp. 240-254 |
| Status: | Peer Reviewed |
| Publication Status: | Published |
| Access rights to Published version: | Restricted or Subscription Access |
| URI: | http://wrap.warwick.ac.uk/id/eprint/46475 |
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