Simon's minimax and optimal and Jung's admissible two-stage designs with or without curtailment
Kunz, Cornelia and Kieser, M.. (2011) Simon's minimax and optimal and Jung's admissible two-stage designs with or without curtailment. Stata Journal, Vol.11 (No.2). pp. 240-254. ISSN 1536-867XFull text not available from this repository.
Official URL: http://www.stata-press.com/journals/
This article describes a new Stata command called simontwostage, which calculates the critical values and sample sizes for two-stage designs for phase II oncology trials. Options are provided to determine the minimax and optimal designs proposed by Simon (1989, Controlled Clinical Trials 10: 1–10) and admissible designs described by Jung et al. (2004, Statistics in Medicine 23: 561–569). Furthermore, nonstochastic and stochastic curtailment rules can be implemented in both stages of the trial, and the properties of the curtailed designs can be examined.
|Item Type:||Journal Article|
|Subjects:||R Medicine > R Medicine (General)|
|Divisions:||Faculty of Medicine > Warwick Medical School > Health Sciences
Faculty of Medicine > Warwick Medical School
|Journal or Publication Title:||Stata Journal|
|Page Range:||pp. 240-254|
|Access rights to Published version:||Restricted or Subscription Access|
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