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The effects of adipose tissue and adipocytokines in human pregnancy
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Valsamakis, Georgios, Kumar, Sudhesh, Creatsas, G. and Mastorakos, George (2010) The effects of adipose tissue and adipocytokines in human pregnancy. Annals of the New York Academy of Sciences, Vol.1205 (No.1). pp. 76-81. doi:10.1111/j.1749-6632.2010.05667.x ISSN 0077-8923.
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Official URL: http://dx.doi.org/10.1111/j.1749-6632.2010.05667.x
Abstract
During pregnancy, important changes take place in maternal metabolism because of the growing fetus and placental formation. The increase in insulin resistance during pregnancy is paralleled by the progressive increase of maternal adipose tissue deposition. This review examines the topography of fat mass deposition during pregnancy in relation to factors such as parity and maternal age that might affect this deposition. We also examine adipose tissue markers, such as pregravid weight and weight gain during pregnancy, and their effect on fetal growth and pregnancy outcomes. In addition, this review studies the possible effects of cytokines that are produced by adipose tissue and the placenta on maternal metabolism and its complications. Finally, we also consider the possible role of maternal adipocytokines and fetal adipocytokines on fetal growth.
Item Type: | Journal Article | ||||
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Subjects: | R Medicine > R Medicine (General) | ||||
Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School | ||||
Journal or Publication Title: | Annals of the New York Academy of Sciences | ||||
Publisher: | Wiley-Blackwell Publishing, Inc. | ||||
ISSN: | 0077-8923 | ||||
Official Date: | September 2010 | ||||
Dates: |
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Volume: | Vol.1205 | ||||
Number: | No.1 | ||||
Page Range: | pp. 76-81 | ||||
DOI: | 10.1111/j.1749-6632.2010.05667.x | ||||
Status: | Peer Reviewed | ||||
Publication Status: | Published | ||||
Access rights to Published version: | Restricted or Subscription Access |
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