Modeling auditory evoked brainstem responses to transient stimuli
Rønne, Filip Munch, Dau, Torsten, Harte, James M. and Elberling, Claus. (2012) Modeling auditory evoked brainstem responses to transient stimuli. The Journal of the Acoustical Society of America, Vol.131 (No.5). pp. 3903-3913. ISSN 0001-4966Full text not available from this repository.
Official URL: http://dx.doi.org/10.1121/1.3699171
A quantitative model is presented that describes the formation of auditory brainstem responses (ABRs) to tone pulses, clicks, and rising chirps as a function of stimulation level. The model computes the convolution of the instantaneous discharge rates using the “humanized” nonlinear auditory-nerve model of Zilany and Bruce [J. Acoust. Soc. Am. 122, 402–417 (2007)] and an empirically derived unitary response function which is assumed to reflect contributions from different cell populations within the auditory brainstem, recorded at a given pair of electrodes on the scalp. It is shown that the model accounts for the decrease of tone-pulse evoked wave-V latency with frequency but underestimates the level dependency of the tone-pulse as well as click-evoked latency values. Furthermore, the model correctly predicts the nonlinear wave-V amplitude behavior in response to the chirp stimulation both as a function of chirp sweeping rate and level. Overall, the results support the hypothesis that the pattern of ABR generation is strongly affected by the nonlinear and dispersive processes in the cochlea.
|Item Type:||Journal Article|
|Subjects:||Q Science > QP Physiology
R Medicine > RF Otorhinolaryngology
T Technology > TA Engineering (General). Civil engineering (General)
T Technology > TK Electrical engineering. Electronics Nuclear engineering
|Divisions:||Faculty of Science > WMG (Formerly the Warwick Manufacturing Group)|
|Journal or Publication Title:||The Journal of the Acoustical Society of America|
|Publisher:||Acoustical Society of America|
|Number of Pages:||11|
|Page Range:||pp. 3903-3913|
|Access rights to Published version:||Restricted or Subscription Access|
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