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Low frequency phase synchronisation analysis of MEG recordings from children with ADHD and controls using single channel ICA
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Demanuele, C., James, C. J., Sonuga-Barke, E. J. S. and Capilla, A. (2008) Low frequency phase synchronisation analysis of MEG recordings from children with ADHD and controls using single channel ICA. In: 4th IET International Conference on Advances in Medical, Signal and Information Processing (MEDSIP), Santa Margherita Ligure, Italy, Jul 14-16, 2008. Published in: Proceedings of the 4th IET International Conference on Advances in Medical, Signal and Information Processing (MEDSIP) pp. 1-4. ISSN 0537-9989, ISBN: 978-0-86341-934-8. doi:10.1049/cp:20080428
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Official URL: http://dx.doi.org/10.1049/cp:20080428
Abstract
It has been suggested that the human brain is intrinsically organised into dynamic, anti-correlated functional networks. This paper presents a study on the so-called default mode network - which is active when the brain is apparently at rest - and on brain activity related to a given task. This work involves the analysis of low frequency magnetoencephalographic recordings of children with Attention Deficit Hyperactivity Disorder (ADHD) and controls performing both attentional as well as perceptual tasks. Single channel independent component analysis is used to isolate low frequency brain signals within the data in the presence of higher frequency brain activity and artifacts. Phase synchrony analysis is then carried out between the components of channels of interest to quantify any interaction between distant brain regions within the default-mode network. Preliminary results show variations in the phase locking between ADHD and controls, and indicate a corresponding change in phase synchrony between the corresponding brain regions at periods of rest and when tasks are being performed.
| Item Type: | Conference Item (Paper) | ||||
|---|---|---|---|---|---|
| Subjects: | R Medicine > R Medicine (General) R Medicine > RJ Pediatrics T Technology > TK Electrical engineering. Electronics Nuclear engineering |
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| Divisions: | Faculty of Science, Engineering and Medicine > Engineering > WMG (Formerly the Warwick Manufacturing Group) | ||||
| Journal or Publication Title: | Proceedings of the 4th IET International Conference on Advances in Medical, Signal and Information Processing (MEDSIP) | ||||
| Publisher: | Institute of Engineering and Technology | ||||
| ISSN: | 0537-9989, ISBN: 978-0-86341-934-8 | ||||
| Official Date: | 2008 | ||||
| Dates: |
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| Page Range: | pp. 1-4 | ||||
| DOI: | 10.1049/cp:20080428 | ||||
| Status: | Not Peer Reviewed | ||||
| Publication Status: | Published | ||||
| Access rights to Published version: | Restricted or Subscription Access | ||||
| Funder: | Comunidad de Madrid, Institute of Sound and Vibration Research, University of Southampton (ISVR), School of Psychology at the University of Southampton | ||||
| Grant number: | HSE/85-04 (Madrid) | ||||
| Conference Paper Type: | Paper | ||||
| Title of Event: | 4th IET International Conference on Advances in Medical, Signal and Information Processing (MEDSIP) | ||||
| Type of Event: | Conference | ||||
| Location of Event: | Santa Margherita Ligure, Italy | ||||
| Date(s) of Event: | Jul 14-16, 2008 | ||||
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