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Tools for metal ion sorting : in vitro evidence for partitioning of zinc and cadmium in C. elegans metallothionein isoforms

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Leszczyszyn, Oksana I., Zeitoun-Ghandour, Sukaina, Stuerzenbaum, Stephen R. and Blindauer, Claudia A.. (2011) Tools for metal ion sorting : in vitro evidence for partitioning of zinc and cadmium in C. elegans metallothionein isoforms. Chemical Communications, Vol.47 (No.1). pp. 448-450. ISSN 1359-7345

Full text not available from this repository.
Official URL: http://dx.doi.org/10.1039/c0cc02188a

Abstract

In vitro evidence for the isoform-specific partitioning of cadmium and zinc ions between the two C. elegans metallothioneins is presented. This observation is discussed in terms of isoform-specific affinities towards zinc and cadmium and the implications of our study on the in vivo roles of C. elegans metallothioneins.

Item Type: Journal Article
Subjects: Q Science > QD Chemistry
Q Science > QP Physiology
Divisions: Faculty of Science > Chemistry
Library of Congress Subject Headings (LCSH): Metallothionein, Metal ions, Homeostasis, Zinc, Cadmium, Electrospray ionization mass spectrometry
Journal or Publication Title: Chemical Communications
Publisher: Royal Society of Chemistry
ISSN: 1359-7345
Date: 2011
Volume: Vol.47
Number: No.1
Number of Pages: 3
Page Range: pp. 448-450
Identification Number: 10.1039/c0cc02188a
Status: Peer Reviewed
Publication Status: Published
Access rights to Published version: Restricted or Subscription Access
Funder: Biotechnology and Biological Sciences Research Council (Great Britain) (BBSRC), Altajir Trust, Advantage West Midlands (AWM), European Regional Development Fund (ERDF)
Grant number: BBE025099 (BBSRC)
References: 1 (a) Y. Chen, R. S. Simmonds, G. L. Sloan and R. Timkovich, J. Biol. Inorg. Chem., 2008, 13, 855–860; (b) C. A. Blindauer, M. D. Harrison, J. A. Parkinson, N. J. Robinson and P. J. Sadler, in 10th Int. Symp. on Metal Ions in Biology and Medicine, ed. P. Collery, I. Maymard, T. Theophanides, L. Khassanova and T. Collery, John Libby Eurotext, 2008, vol. 10, pp. 167–173. 2 (a) O. I. Leszczyszyn and C. A. Blindauer, Mol. BioSyst., 2010, 6, 1592–1603; (b) P. Palumaa, O. Njunkova, L. Pokras, E. Eriste, H. Jo¨ rnvall and R. Sillard, FEBS Lett., 2002, 527, 76–80. 3 R. Kothinti, A. Blodgett, N. M. Tabatabai and D. H. Petering, Chem. Res. Toxicol., 2010, 23, 405–412. 4 F. Thevenod, Toxicol. Appl. Pharmacol., 2009, 238, 221–239. 5 M. l. Viaua, J. Gastaldo, Z. Bencokova, A. Joubert and N. Foray, Mutat. Res., 2008, 365, 13–21. 6 N. M. Tabatabai, S. S. Blumenthal and D. H. Petering, Toxicology, 2005, 207, 369–382. 7 K. Balamurugan and W. Schaffner, Met. Ions Life Sci., 2009, 5, 31–49. 8 M. Nordberg and G. F. Nordberg, Met. Ions Life Sci., 2009, 5, 1–29. 9 D. Egli, A. Selvaraj, H. Yepiskoposyan, B. Zhang, E. Hafen, O. Georgiev and W. Schaffner, EMBO J., 2003, 22, 100–108. 10 R. Bofill, M. Capdevila and S. Atrian, Metallomics, 2009, 1, 229–234. 11 J. H. Freedman, L. W. Slice, D. Dixon, A. Fire and C. S. Rubin, J. Biol. Chem., 1993, 268, 554–564. 12 S. C. Swain, K. Keusekotten, R. Baumeister and S. R. Sturzenbaum, J. Mol. Biol., 2004, 341, 951–959. 13 S. Zeitoun-Ghandour, J. M. Charnock, M. E. Hodson, O. I. Leszczyszyn, C. A. Blindauer and S. R. Stu¨ rzenbaum, FEBS J., 2010, 277, 2531–2542. 14 P. Palumaa, I. Tammiste, K. Kruusel, L. Kangur, H. Jo¨ rnvall and R. Sillard, Biochim. Biophys. Acta, Proteins Proteomics, 2005, 1747, 205–211. 15 R. Bofill, R. Orihuela, M. Romagosa, J. Domenech, S. Atrian and M. Capdevila, FEBS J., 2009, 276, 7040–7069. 16 C. A. Blindauer, N. C. Polfer, S. E. Keiper, M. D. Harrison, N. J. Robinson, P. R. R. Langridge-Smith and P. J. Sadler, J. Am. Chem. Soc., 2003, 125, 3226–3227. 17 B. A. Krizek, D. L. Merkle and J. M. Berg, Inorg. Chem., 1993, 32, 937–940. 18 D. W. Hasler, L. T. Jensen, O. Zerbe, D. R. Winge and M. Vasak, Biochemistry, 2000, 39, 14567–14575.
URI: http://wrap.warwick.ac.uk/id/eprint/4727

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