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Tools for metal ion sorting : in vitro evidence for partitioning of zinc and cadmium in C. elegans metallothionein isoforms
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Leszczyszyn, Oksana I., Zeitoun-Ghandour, Sukaina, Stuerzenbaum, Stephen R. and Blindauer, Claudia A.. (2011) Tools for metal ion sorting : in vitro evidence for partitioning of zinc and cadmium in C. elegans metallothionein isoforms. Chemical Communications, Vol.47 (No.1). pp. 448-450. ISSN 1359-7345
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Official URL: http://dx.doi.org/10.1039/c0cc02188a
Abstract
In vitro evidence for the isoform-specific partitioning of cadmium and zinc ions between the two C. elegans metallothioneins is presented. This observation is discussed in terms of isoform-specific affinities towards zinc and cadmium and the implications of our study on the in vivo roles of C. elegans metallothioneins.
| Item Type: | Journal Article |
|---|---|
| Subjects: | Q Science > QD Chemistry Q Science > QP Physiology |
| Divisions: | Faculty of Science > Chemistry |
| Library of Congress Subject Headings (LCSH): | Metallothionein, Metal ions, Homeostasis, Zinc, Cadmium, Electrospray ionization mass spectrometry |
| Journal or Publication Title: | Chemical Communications |
| Publisher: | Royal Society of Chemistry |
| ISSN: | 1359-7345 |
| Date: | 2011 |
| Volume: | Vol.47 |
| Number: | No.1 |
| Number of Pages: | 3 |
| Page Range: | pp. 448-450 |
| Identification Number: | 10.1039/c0cc02188a |
| Status: | Peer Reviewed |
| Publication Status: | Published |
| Access rights to Published version: | Restricted or Subscription Access |
| Funder: | Biotechnology and Biological Sciences Research Council (Great Britain) (BBSRC), Altajir Trust, Advantage West Midlands (AWM), European Regional Development Fund (ERDF) |
| Grant number: | BBE025099 (BBSRC) |
| References: | 1 (a) Y. Chen, R. S. Simmonds, G. L. Sloan and R. Timkovich, J. Biol. Inorg. Chem., 2008, 13, 855–860; (b) C. A. Blindauer, M. D. Harrison, J. A. Parkinson, N. J. Robinson and P. J. Sadler, in 10th Int. Symp. on Metal Ions in Biology and Medicine, ed. P. Collery, I. Maymard, T. Theophanides, L. Khassanova and T. Collery, John Libby Eurotext, 2008, vol. 10, pp. 167–173. 2 (a) O. I. Leszczyszyn and C. A. Blindauer, Mol. BioSyst., 2010, 6, 1592–1603; (b) P. Palumaa, O. Njunkova, L. Pokras, E. Eriste, H. Jo¨ rnvall and R. Sillard, FEBS Lett., 2002, 527, 76–80. 3 R. Kothinti, A. Blodgett, N. M. Tabatabai and D. H. Petering, Chem. Res. Toxicol., 2010, 23, 405–412. 4 F. Thevenod, Toxicol. Appl. Pharmacol., 2009, 238, 221–239. 5 M. l. Viaua, J. Gastaldo, Z. Bencokova, A. Joubert and N. Foray, Mutat. Res., 2008, 365, 13–21. 6 N. M. Tabatabai, S. S. Blumenthal and D. H. Petering, Toxicology, 2005, 207, 369–382. 7 K. Balamurugan and W. Schaffner, Met. Ions Life Sci., 2009, 5, 31–49. 8 M. Nordberg and G. F. Nordberg, Met. Ions Life Sci., 2009, 5, 1–29. 9 D. Egli, A. Selvaraj, H. Yepiskoposyan, B. Zhang, E. Hafen, O. Georgiev and W. Schaffner, EMBO J., 2003, 22, 100–108. 10 R. Bofill, M. Capdevila and S. Atrian, Metallomics, 2009, 1, 229–234. 11 J. H. Freedman, L. W. Slice, D. Dixon, A. Fire and C. S. Rubin, J. Biol. Chem., 1993, 268, 554–564. 12 S. C. Swain, K. Keusekotten, R. Baumeister and S. R. Sturzenbaum, J. Mol. Biol., 2004, 341, 951–959. 13 S. Zeitoun-Ghandour, J. M. Charnock, M. E. Hodson, O. I. Leszczyszyn, C. A. Blindauer and S. R. Stu¨ rzenbaum, FEBS J., 2010, 277, 2531–2542. 14 P. Palumaa, I. Tammiste, K. Kruusel, L. Kangur, H. Jo¨ rnvall and R. Sillard, Biochim. Biophys. Acta, Proteins Proteomics, 2005, 1747, 205–211. 15 R. Bofill, R. Orihuela, M. Romagosa, J. Domenech, S. Atrian and M. Capdevila, FEBS J., 2009, 276, 7040–7069. 16 C. A. Blindauer, N. C. Polfer, S. E. Keiper, M. D. Harrison, N. J. Robinson, P. R. R. Langridge-Smith and P. J. Sadler, J. Am. Chem. Soc., 2003, 125, 3226–3227. 17 B. A. Krizek, D. L. Merkle and J. M. Berg, Inorg. Chem., 1993, 32, 937–940. 18 D. W. Hasler, L. T. Jensen, O. Zerbe, D. R. Winge and M. Vasak, Biochemistry, 2000, 39, 14567–14575. |
| URI: | http://wrap.warwick.ac.uk/id/eprint/4727 |
Data sourced from Thomson Reuters' Web of Knowledge
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