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Evaluation of the antimicrobial effect of super-oxidized water (Sterilox (R)) and sodium hypochlorite against Enterococcus faecalis in a bovine root canal model

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Rossi-Fedele, Giampiero, de Figueiredo, Jose Antonio Poli, Steier, Liviu, Canullo, Luigi, Steier, Gabriela and Roberts, Adam P.. (2010) Evaluation of the antimicrobial effect of super-oxidized water (Sterilox (R)) and sodium hypochlorite against Enterococcus faecalis in a bovine root canal model. Journal of Applied Oral Science, Vol.18 (No.5). pp. 498-502. ISSN 1678-7757

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Official URL: http://www.scielo.br/scielo.php?script=sci_serial&...

Abstract

Ideally root canal irrigants should have, amongst other properties, antimicrobial action associated with a lack of toxicity against periapical tissues. Sodium hypochlorite (NaOCl) is a widely used root canal irrigant, however it has been shown to have a cytotoxic effect on vital tissue and therefore it is prudent to investigate alternative irrigants. Sterilox's Aquatine Alpha Electrolyte (R) belongs to the group of the super-oxidized waters; it consists of a mixture of oxidizing substances, and has been suggested to be used as root canal irrigant. Super-oxidized waters have been shown to provide efficient cleaning of root canal walls, and have been proposed to be used for the disinfection of medical equipment. Objective: To compare the antimicrobial action against Enterococcus faecalis of NaOCl, Optident Sterilox Electrolyte Solution (R) and Sterilox's Aquatine Alpha Electrolyte (R) when used as irrigating solutions in a bovine root canal model. Methodology: Root sections were prepared and inoculated with E. faecalis JH2-2. After 10 days of incubation the root canals were irrigated using one of three solutions (NaOCl, Optident Sterilox Electrolyte Solution (R) and Sterilox's Aquatine Alpha Electrolyte (R)) and subsequently sampled by grinding dentin using drills. The debris was placed in BHI broth and dilutions were plated onto fresh agar plates to quantify growth. Results: Sodium hypochlorite was the only irrigant to eliminate all bacteria. When the dilutions were made, although NaOCl was still statistically superior, Sterilox's Aquatine Alpha Electrolyte (R) solution was superior to Optident Sterilox Electrolyte Solution (R). Conclusions: Under the conditions of this study Sterilox's Aquatine Alpha Electrolyte (R) appeared to have significantly more antimicrobial action compared to the Optident Sterilox Electrolyte Solution (R) alone, however NaOCl was the only solution able to consistently eradicate E. faecalis in the model.

Item Type: Journal Article
Subjects: R Medicine > RK Dentistry
Divisions: Faculty of Medicine > Warwick Medical School
Journal or Publication Title: Journal of Applied Oral Science
Publisher: Universidade de Sao Paulo Faculdade de Odontologia de Bauru
ISSN: 1678-7757
Date: September 2010
Volume: Vol.18
Number: No.5
Number of Pages: 5
Page Range: pp. 498-502
Status: Peer Reviewed
Publication Status: Published
Access rights to Published version: Open Access
URI: http://wrap.warwick.ac.uk/id/eprint/4744

Data sourced from Thomson Reuters' Web of Knowledge

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