Short sleep duration is associated with the development of impaired fasting glucose : the Western New York health study
Rafalson, Lisa, Donahue, Richard P., Stranges, Saverio, LaMonte, Michael J., Dmochowski, Jacek, Dorn, Joan M. and Trevisan, Maurizio. (2010) Short sleep duration is associated with the development of impaired fasting glucose : the Western New York health study. Annals of Epidemiology, Vol.20 (No.12). pp. 883-889. ISSN 1047-2797Full text not available from this repository.
Official URL: http://dx.doi.org/10.1016/j.annepidem.2010.05.002
PURPOSE: To examine whether sleep duration was associated with incident-impaired fasting glucose (IFG) over 6 years of follow-up in the Western New York Health Study.
METHODS: Participants (N = 1,455, 68% response rate) who were free of type 2 diabetes and known cardiovascular disease at baseline (1996-2001) were reexamined in the period 2003-2004. A nested case-control study was conducted. Cases had fasting plasma glucose (FPG) less than 100 mg/dL at baseline and 100 to 125 mg/dL at follow-up: controls (n = 272) had FPG less than 100 mg/dL at both exams. Cases (n = 91) were individually matched to three controls (n 272) on sex, race, and year of study enrollment. Average sleep duration was categorized as short ( < 6 hours), mid-range (6 to 8 hours), and long ( > 8 hours).
RESULTS: In multivariate conditional logistic regression after adjustment for several diabetes risk factors, the odds ratio (OR) of IFG among short sleepers was 3.0 (95% confidence limit [CL]: 1.05, 8.59) compared to mid-range sleepers. There was no association between long sleep and IFG: OR 1.6 (95% CL: 0.45, 5.42). Adjustment for insulin resistance attenuated the association only among short sleepers: OR 2.5 (95% CL: 0.83, 7.46).
CONCLUSIONS: Short sleep duration was associated with an elevated risk of IFG. Insulin resistance appears to mediate this association. Ann Epidemiol 2010;20:883-889. (C) 2010 Elsevier Inc. All rights reserved.
|Item Type:||Journal Article|
|Subjects:||Q Science > QP Physiology
R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine
|Divisions:||Faculty of Medicine > Warwick Medical School > Health Sciences
Faculty of Medicine > Warwick Medical School
|Library of Congress Subject Headings (LCSH):||Glucose -- Metabolism, Glucose -- Physiological effect, Case-control method, Sleep, Sleep disorders|
|Journal or Publication Title:||Annals of Epidemiology|
|Publisher:||Elsevier Science Inc.|
|Official Date:||December 2010|
|Number of Pages:||7|
|Page Range:||pp. 883-889|
|Access rights to Published version:||Restricted or Subscription Access|
|Funder:||National Institutes of Health (U.S.) (NIH), National Institute of Diabetes and Digestive and Kidney Diseases (U.S.) (NIDDK)|
|Grant number:||RO1 DK60587 (NIDDK)|
1. Penev PD. Sleep deprivation and energy metabolism: to sleep, perchance
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