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Opinions on drug interaction sources in anticancer treatments and parameters for an oncology-specific database by pharmacy practitioners in Asia
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Yap, Kevin Yi-Lwern, Chan, Alexandre and Chui, Wai Keung (2010) Opinions on drug interaction sources in anticancer treatments and parameters for an oncology-specific database by pharmacy practitioners in Asia. Health Services Insights, Vol.3 . pp. 1-12. doi:10.4137/HSI.S3679 ISSN 1178-6329.
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Official URL: http://dx.doi.org/10.4137/HSI.S3679
Abstract
Cancer patients undergoing chemotherapy are particularly susceptible to drug-drug interactions (DDIs). Practitioners should keep themselves updated with the most current DDI information, particularly involving new anticancer drugs (ACDs). Databases can be useful to obtain up-to-date DDI information in a timely and efficient manner. Our objective was to investigate the DDI information sources of pharmacy practitioners in Asia and their views on the usefulness of an oncology-specific database for ACD interactions. A qualitative, cross-sectional survey was done to collect information on the respondents’ practice characteristics, sources of DDI information and parameters useful in an ACD interaction database. Response rate was 49%. Electronic databases (70%), drug interaction textbooks (69%) and drug compendia (64%) were most commonly used. Majority (93%) indicated that a database catering towards ACD interactions was useful. Essential parameters that should be included in the database were the mechanism and severity of the detected interaction, and the presence of a management plan (98% each). This study has improved our understanding on the usefulness of various DDI information sources for ACD interactions among pharmacy practitioners in Asia. An oncology-specific DDI database targeting ACD interactions is definitely attractive for clinical practice.
| Item Type: | Journal Article | ||||
|---|---|---|---|---|---|
| Subjects: | R Medicine > RC Internal medicine > RC0254 Neoplasms. Tumors. Oncology (including Cancer) R Medicine > RM Therapeutics. Pharmacology R Medicine > RS Pharmacy and materia medica |
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| Divisions: | Faculty of Science, Engineering and Medicine > Engineering > WMG (Formerly the Warwick Manufacturing Group) | ||||
| Journal or Publication Title: | Health Services Insights | ||||
| Publisher: | Libertas Academica Ltd. | ||||
| ISSN: | 1178-6329 | ||||
| Official Date: | 11 February 2010 | ||||
| Dates: |
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| Volume: | Vol.3 | ||||
| Number of Pages: | 12 | ||||
| Page Range: | pp. 1-12 | ||||
| DOI: | 10.4137/HSI.S3679 | ||||
| Status: | Peer Reviewed | ||||
| Publication Status: | Published | ||||
| Access rights to Published version: | Open Access (Creative Commons) | ||||
| Funder: | National University of Singapore |
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