Hierarchically structured titanium foams for tissue scaffold applications
Singh, R., Lee, P. D., Jones, J. R., Poologasundarampillai, G., Post, T., Lindley, T. C. and Dashwood, R. J.. (2010) Hierarchically structured titanium foams for tissue scaffold applications. Acta Biomaterialia, Vol.6 (No.12). pp. 4596-4604. ISSN 1742-7061Full text not available from this repository.
Official URL: http://dx.doi.org/10.1016/j.actbio.2010.06.027
We present a novel route for producing a new class of titanium foams for use in biomedical implant applications. These foams are hierarchically porous, with both the traditional large (>300 mu m) highly interconnected pores and, uniquely, wall struts also containing micron scale (0.5-5 mu m) interconnected porosities. The fabrication method consists of first producing a porous oxide precursor via a gel casting method, followed by electrochemical reduction to produce a metallic foam. This method offers the unique ability to tailor the porosity at several scales independently, unlike traditional space-holder techniques. Reducing the pressure during foam setting increased the macro-pore size. The intra-strut pore size (and percentage) can be controlled independently of macro-pore size by altering the ceramic loading and sintering temperature during precursor production. Typical properties for an 80% porous Ti foam were a modulus of similar to 1 GPa, a yield strength of 8 MPa and a permeability of 350 Darcies, all of which are in the range required for biomedical implant applications. We also demonstrate that the micron scale intra-strut porosities can be exploited to allow infiltration of bioactive materials using a novel bioactive silica-polymer composite, resulting in a metal-bioactive silica-polymer composite. (C) 2010 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.
|Item Type:||Journal Article|
|Divisions:||Faculty of Science > WMG (Formerly the Warwick Manufacturing Group)|
|Journal or Publication Title:||Acta Biomaterialia|
|Publisher:||Elsevier Science Ltd.|
|Number of Pages:||9|
|Page Range:||pp. 4596-4604|
|Access rights to Published version:||Restricted or Subscription Access|
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