The Library
Organometallic ruthenium and iridium transfer-hydrogenation catalysts using coenzyme NADH as a cofactor
Tools
Tools
Tools
Betanzos-Lara, Soledad, Liu, Zhe (Researcher in chemistry), Habtemariam, Abraha, Pizarro, Ana M., Qamar, Bushra and Sadler, P. J.. (2012) Organometallic ruthenium and iridium transfer-hydrogenation catalysts using coenzyme NADH as a cofactor. Angewandte Chemie International Edition, Vol.51 (No.16). pp. 3897-3900. ISSN 1433-7851
Full text not available from this repository.
Official URL: http://dx.doi.org/10.1002/anie.201108175
Abstract
Artificial enzymes: Half-sandwich arene ruthenium(II) and cyclopentadienyl iridium(III) complexes containing N,N-chelated ligands can use NADH as a source of hydride for the reduction of ketones (see picture). Moreover, cyclopentadienyl phenanthroline iridium(III) derivatives at micromolar concentrations are robust catalysts for the production of H2 from NADH in water and can raise the NAD+/NADH ratio in cancer cells.
| Item Type: | Journal Article |
|---|---|
| Divisions: | Faculty of Science > Chemistry |
| Journal or Publication Title: | Angewandte Chemie International Edition |
| Publisher: | Wiley - V C H Verlag GmbH & Co. KGaA |
| ISSN: | 1433-7851 |
| Date: | 2012 |
| Volume: | Vol.51 |
| Number: | No.16 |
| Page Range: | pp. 3897-3900 |
| Identification Number: | 10.1002/anie.201108175 |
| Status: | Peer Reviewed |
| Publication Status: | Published |
| URI: | http://wrap.warwick.ac.uk/id/eprint/49048 |
Actions (login required)
 |
View Item |
