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Structural changes in freshwater fish and chironomids exposed to bacterial exotoxins
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Lewis, J. W., Morley, N. J., Ahmad, Mark, Challis, Gregory L., Wright, R., Bicker, R. and Morritt, D.. (2012) Structural changes in freshwater fish and chironomids exposed to bacterial exotoxins. Ecotoxicology and Environmental Safety, Vol.80 . pp. 37-44. ISSN 0147-6513
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Official URL: http://dx.doi.org/10.1016/j.ecoenv.2012.02.006
Abstract
Mass fish mortalities have been reported in the past decade from British waters, often coinciding with blooms of filamentous actinobacteria, particularly strains of Streptomyces griseus. The present study has shown that some fractions of the exudate of S. griseus, prepared after a series of high pressure liquid chromatography (HPLC) separations, and analysed with liquid chromatography mass spectrometry (LC–MS), induced pathological changes to the gills of carp and/or tench fry following exposure under laboratory conditions up to 96 h Similar changes were induced by streptomycin, a secondary metabolite of S. griseus, and these included loss of microridging and fusion of secondary lamellae, with carp fry in the case of the exudate of S. griseus being more sensitive than tench fry, especially with exposure to fraction 9 and selected sub-fractions of 9. Some deformities using a severity index were also observed in the head capsule of larvae of the non-biting midge Chironomus riparius, including loss and splitting of teeth on the mentum. The results are discussed in relation to further identification of metabolites derived from samples of the organic filtrate of S. griseus and implications for the functioning of freshwater ecosystems.
| Item Type: | Journal Article |
|---|---|
| Subjects: | Q Science > QD Chemistry |
| Divisions: | Faculty of Science > Chemistry |
| Journal or Publication Title: | Ecotoxicology and Environmental Safety |
| Publisher: | Academic Press |
| ISSN: | 0147-6513 |
| Official Date: | 1 June 2012 |
| Volume: | Vol.80 |
| Page Range: | pp. 37-44 |
| Identification Number: | 10.1016/j.ecoenv.2012.02.006 |
| Status: | Peer Reviewed |
| Publication Status: | Published |
| Access rights to Published version: | Restricted or Subscription Access |
| URI: | http://wrap.warwick.ac.uk/id/eprint/49441 |
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