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The clinical effectiveness and cost-effectiveness of computed tomography screening for lung cancer : systematic reviews
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Black, C. (Corrinda), Bagust, A., Boland, A., Walker, S., McLeod, C., De Verteuil, R. (Robyn), Ayres, J. G., Bain, L. (Lynda), Thomas, Sian, Godden, D. J. (David John) and Waugh, Norman (2006) The clinical effectiveness and cost-effectiveness of computed tomography screening for lung cancer : systematic reviews. Health Technology Assessment, Vol.10 (No.3). ISSN 1366-5278.
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Official URL: http://www.hta.ac.uk/pdfexecs/summ1003.pdf
Abstract
Screening for lung cancer has been the subject of
debate for the past three decades. This has largely
stemmed from the results of chest X-ray screening
studies where improvements in survival were
obtained but without reductions in disease-specific,
or total, mortality. The debate raises two issues:
the design of studies to evaluate screening for
lung cancer, in particular the choice of
comparator; and the potential role of overdiagnosis of well-differentiated, slow-growing
tumours that would not have led to symptoms or
death in the lifetime of the affected patient.
Lung cancer is the leading cause of death from
cancer in the UK, killing approximately 34,000
people per year. By the time symptoms develop,
the tumour is often at an advanced stage and the
prognosis is bleak. Treatment at a less advanced
stage of disease with surgical resection has been
shown to substantially reduce mortality.
Screening would be attractive if it could detect
presymptomatic lung cancer at a stage when
surgical intervention is feasible.
Item Type: | Journal Article | ||||
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Subjects: | R Medicine > RC Internal medicine > RC0254 Neoplasms. Tumors. Oncology (including Cancer) | ||||
Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences > Population, Evidence & Technologies (PET) > Warwick Evidence Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School |
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Library of Congress Subject Headings (LCSH): | Lungs -- Cancer -- Diagnosis, Tomography -- Cost effectiveness | ||||
Journal or Publication Title: | Health Technology Assessment | ||||
Publisher: | National Coordinating Centre for Health Technology Assessment | ||||
ISSN: | 1366-5278 | ||||
Official Date: | 2006 | ||||
Dates: |
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Volume: | Vol.10 | ||||
Number: | No.3 | ||||
Status: | Peer Reviewed | ||||
Publication Status: | Published | ||||
Access rights to Published version: | Open Access (Creative Commons) | ||||
Date of first compliant deposit: | 22 December 2015 | ||||
Date of first compliant Open Access: | 22 December 2015 |
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