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The glycopolymer code : synthesis of glycopolymers and multivalent carbohydrate-lectin interactions
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Becer, C. Remzi (2012) The glycopolymer code : synthesis of glycopolymers and multivalent carbohydrate-lectin interactions. Macromolecular Rapid Communications, Vol.33 (No.9). pp. 742-752. doi:10.1002/marc.201200055 ISSN 1022-1336.
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Official URL: http://dx.doi.org/10.1002/marc.201200055
Abstract
Glycopolymers are becoming more and more important in understanding biological interactions due to their unique recognition properties. Macromolecules with different chain lengths, compositions and architectures provide enormous diversity in the formation of primary and secondary structures that have a major effect on multivalent binding to lectins. It is crucial to control the precise structure of macromolecules to achieve specific and selective carbohydrate-lectin binding. The use of advanced synthesis techniques to prepare well-defined glycopolymers and selected advanced analytical techniques to study multivalent interactions are highlighted in this Feature Article. Glycopolymers have unique recognition properties and can be used in various bioapplications. The well-defined structures of glycopolymers effect their binding to proteins significantly. It is crucial to gain absolute control over their structure to control specific carbohydrate-lectin interactions. These interactions can be best determined by advanced techniques, QCM and SPR. © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
| Item Type: | Journal Article | ||||
|---|---|---|---|---|---|
| Divisions: | Faculty of Science, Engineering and Medicine > Science > Chemistry | ||||
| Journal or Publication Title: | Macromolecular Rapid Communications | ||||
| Publisher: | Wiley - V C H Verlag GmbH & Co. KGaA | ||||
| ISSN: | 1022-1336 | ||||
| Official Date: | 14 May 2012 | ||||
| Dates: |
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| Volume: | Vol.33 | ||||
| Number: | No.9 | ||||
| Page Range: | pp. 742-752 | ||||
| DOI: | 10.1002/marc.201200055 | ||||
| Status: | Peer Reviewed | ||||
| Publication Status: | Published | ||||
| Access rights to Published version: | Restricted or Subscription Access |
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