Coates, Mary E. and Beynon, Jim (2010) Hyaloperonospora arabidopsidis as a pathogen model. Annual Review of Phytopathology, Vol.48 . pp. 329-345. doi:10.1146/annurev-phyto-080508-094422

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Abstract

Hyaloperonospora arabidopsidis, a downy mildew pathogen of the model plant Arabidopsis, has been very useful in the understanding of the relationship between oomycetes and their host plants. This naturally co-evolving pathosystem contains an amazing level of genetic diversity in host resistance and pathogen avirulence proteins. Oomycete effectors identified to date contain a targeting motif, RXLR, enabling effector entry into the host cell. The availability of the H. arabidopsidis genome sequence has enabled bioinformatic analyses to identify at least 130 RXLR effectors, potentially used to quell the host's defense mechanism and manipulate other host cellular processes. Currently, these effectors are being used to reveal their targets in the host cell. Eventually this will result in an understanding of the mechanisms used by a pathogen to sustain a biotrophic relationship with a plant.

Item Type:	Journal Item
Subjects:	S Agriculture > SB Plant culture
Divisions:	Faculty of Science > Life Sciences (2010- )
Series Name:	Annual Review of Phytopathology
Journal or Publication Title:	Annual Review of Phytopathology
Publisher:	Annual Reviews
ISSN:	0066-4286
Official Date:	2010
Dates:	Date Event 2010 Published
Volume:	Vol.48
Number of Pages:	17
Page Range:	pp. 329-345
DOI:	10.1146/annurev-phyto-080508-094422
Status:	Peer Reviewed
Publication Status:	Published
Access rights to Published version:	Restricted or Subscription Access

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