Dilly, Suzanne J., Beecham, Matthew P., Brown, Steven P., Griffin, John M., Clark, Andrew J., Griffin, Craig D., Marshall, Jacqueline, Napier, Richard M. , Taylor, Paul C. and Marsh, Andrew. (2006) Novel tertiary amine oxide surfaces that resist non-specific protein adsorption. Langmuir, Vol.22 (No.19). pp. 8144-8150. ISSN 1520-5827

Text WRAOP_Marsh_ProteinResistantSurfacesLangmuir17-3-06.pdf - Submitted Version Restricted to Repository staff only Download (389Kb)

Abstract

Novel surfaces derivatised with tertiary amine oxides have been prepared and tested for their ability to resist non-specific protein adsorption. The oxidation of tertiary amines supported on triazine units was carried out using m-cpba to give a format allowing conjugation of biologically active ligands alongside them. Adsorption to these surfaces was tested and compared with adsorption to a set of commercial and custom oligo- / polyethylene glycol (OEG/PEG) supports by challenging them with a protein display library presented on bacteriophage λ. The new class of amine oxide surfaces is found to equal or exceed the performance of the OEG/PEG supports in the prevention of non-specific binding.

Item Type:	Journal Article
Subjects:	Q Science > QD Chemistry Q Science > QH Natural history > QH301 Biology
Divisions:	Faculty of Science > Chemistry Faculty of Science > Physics Faculty of Science > Life Sciences (2010- ) > Warwick HRI (2004-2010)
Library of Congress Subject Headings (LCSH):	Proteins -- Absorption and adsorption, Amines
Journal or Publication Title:	Langmuir
Publisher:	American Chemical Society
ISSN:	1520-5827
Date:	2006
Volume:	Vol.22
Number:	No.19
Number of Pages:	7
Page Range:	pp. 8144-8150
Identification Number:	10.1021/la060743j
Status:	Peer Reviewed
Publication Status:	Published
Access rights to Published version:	Restricted or Subscription Access
Funder:	Biotechnology and Biological Sciences Research Council (Great Britain) (BBSRC), Engineering and Physical Sciences Research Council (EPSRC), Royal Society (Great Britain)
Grant number:	GR 88/EGM17690 (BBSRC)
References:	(1) Kane, R. S.; Deschatelets, P.; Whitesides, G. M. Langmuir 2003, 19, 2388- 2391. (2) Mrksich, M.; Chen, C. S.; Xia, Y. N.; Dike, L. E.; Ingber, D. E.; Whitesides, G. M. Proc. Natl. Acad. Sci. USA 1996, 93, 10775-10778. (3) Statz, A. R.; Meagher, R. J.; Barron, A. E.; Messersmith, P. B. J. Am. Chem. Soc. 2005, 127, 7972-7973. (4) Heuberger, R.; Sukhorukov, G.; Voros, J.; Textor, M.; Mohwald, H. Adv. Funct. Mater. 2005, 15, 357-366. (5) Lan, S.; Veiseh, M.; Zhang, M. Q. Biosensors & Bioelectronics 2005, 20, 1697-1708. (6) Herrwerth, S.; Rosendahl, T.; Feng, C.; Fick, J.; Eck, W.; Himmelhaus, M.; Dahint, R.; Grunze, M. Langmuir 2003, 19, 1880-1887. (7) Barrett, D. A.; Hartshorne, M. S.; Hussain, M. A.; Shaw, P. N.; Davies, M. C. Anal. Chem. 2001, 73, 5232-5239. (8) Sche, P. P.; McKenzie, K. M.; White, J. D.; Austin, D. J. Chem. Biol. 1999, 6, 707-716. (9) Shimizu, S.; Smith, D. J. J. Chem. Phys. 2004, 121, 1148-1154. (10) Baskakov, I.; Bolen, D. W. J. Biol. Chem. 1998, 273, 4831-4834. (11) Yancey, P. H.; Clark, M. E.; Hand, S. C.; Bowlus, R. D.; Somero, G. N. Science 1982, 217, 1214-1222. (12) Baskakov, I. V.; Kumar, R.; Srinivasan, G.; Ji, Y. S.; Bolen, D. W.; Thompson, E. B. Faseb J. 1999, 13, A1486-A1486. (13) Auton, M.; Bolen, D. W. Biochemistry 2004, 43, 1329-1342. (14) Bolen, D. W. Methods in Enzymology 2004, 34, 312-322. (15) Bennion, B. J.; DeMarco, M. L.; Daggett, V. Biochemistry 2004, 43, 12955- 12963. (16) Lee, J. H.; Lee, H. B.; Andrade, J. D. Prog. Polym. Sci. 1995, 20, 1043-1079. (17) Mrksich, M.; Whitesides, G. M. Ann. Rev. Biophys. Biomol. Struct. 1996, 25, 55-78. (18) Unsworth, L. D.; Sheardown, H.; Brash, J. L. Langmuir 2005, 21, 1036-1041. (19) Herrwerth, S.; Eck, W.; Reinhardt, S.; Grunze, M. J. Am. Chem. Soc. 2003, 125, 9359-9366. (20) Heuberger, M.; Drobek, T.; Voros, J. Langmuir 2004, 20, 9445-9448. (21) Kim, H. I.; Kushmerick, J. G.; Houston, J. E.; Bunker, B. C. Langmuir 2003, 19, 9271-9275. (22) Li, L. Y.; Chen, S. F.; Zheng, J.; Ratner, B. D.; Jiang, S. Y. J. Phys. Chem. B 2005, 109, 2934-2941. (23) Ruegsegger, M. A.; Marchant, R. E. J. Biomed. Mater. Res. 2001, 56, 159- 167. (24) Jon, S. Y.; Seong, J. H.; Khademhosseini, A.; Tran, T. N. T.; Laibinis, P. E.; Langer, R. Langmuir 2003, 19, 9989-9993. (25) Irvine, D. J.; Mayes, A. M.; Satija, S. K.; Barker, J. G.; Sofia-Allgor, S. J.; Griffith, L. G. J. Biomed. Mater. Res. 1998, 40, 498-509. (26) Dalsin, J. L.; Lin, L. J.; Tosatti, S.; Voros, J.; Textor, M.; Messersmith, P. B. Langmuir 2005, 21, 640-646. (27) Drobek, T.; Spencer, N. D.; Heuberger, M. Macromolecules 2005, 38, 5254- 5259. (28) Prime, K. L.; Whitesides, G. M. J. Am. Chem. Soc. 1993, 115, 10714-10721. (29) Chapman, R. G.; Ostuni, E.; Takayama, S.; Holmlin, R. E.; Yan, L.; Whitesides, G. M. J. Am. Chem. Soc. 2000, 122, 8303-8304. (30) Fukai, R.; Dakwa, P. H. R.; Chen, W. J. Polym. Sci. Part A-Polym. Chem. 2004, 42, 5389-5400. (31) Siegers, C.; Biesalski, M.; Haag, R. Chem. Eur. J. 2004, 10, 2831-2838. (32) Metzke, M.; Bai, J. Z.; Guan, Z. B. J. Am. Chem. Soc. 2003, 125, 7760-7761. (33) Bell, M. PhD Thesis; Horticulture Research Institute: Wellesbourne, 2002. (34) Marsh, A.; Carlisle, S. J.; Smith, S. C. Tetrahedron Lett. 2001, 42, 493-496. (35) Dilly, S. J.; Carlisle, S. J.; Clark, A. J.; Shepherd, A. R.; Smith, S. C.; Taylor, P. C.; Marsh, A. J. Polym. Sci. Part A-Polym. Chem. 2006, 44, 2248-2259. (36) Thurston, J. T.; Dudley, J. R.; Kaiser, D. W.; Hechenbleikner, I.; Schaefer, F. C.; Holm-Hansen, D. J. Am. Chem. Soc. 1951, 73, 2981-2983. (37) Sambrook, J.; Fritsch, E. F.; Maniatis, T. Molecular Cloning - A Laboratory Manual; 2nd Ed.; Cold Spring Harbour Press, New York: 1989. (38) Hediger, S.; Meier, B. H.; Kurur, N. D.; Bodenhausen, G.; Ernst, R. R. Chem. Phys. Lett. 1994, 223, 283-288. (39) Metz, G.; Wu, X. L.; Smith, S. O. J. Magn. Reson. Ser. A 1994, 110. (40) Bennett, A. E.; Rienstra, C. M.; Auger, M.; Lakshmi, K. V.; Griffin, R. G. J. Chem. Phys. 1995, 103, 6951-6958.
URI:	http://wrap.warwick.ac.uk/id/eprint/50602

Request changes to a record

Actions (login required)

View Item