Nucleobase containing synthetic polymers : advancing biomimicry via controlled synthesis and self-assembly
McHale, Ronan and O’Reilly, Rachel K.. (2012) Nucleobase containing synthetic polymers : advancing biomimicry via controlled synthesis and self-assembly. Macromolecules, Vol.45 (No.19). pp. 7665-7675. ISSN 0024-9297Full text not available from this repository.
Official URL: http://dx.doi.org/10.1021/ma300895u
The hydrogen-bonding recognition interactions of nucleobases are a fundamental property of nucleic acid chemistry and associated transcription, translation, and replication functions. Nucleobase interactions are central in protein biosynthesis, yielding sequence- and stereospecific macromolecules capable of assembly into precisely defined, complex shapes and morphologies that make up the machinery of life. As the understanding of nucleobases and their significance developed in the past century, chemists have inevitably sought to extend their function from a biological setting onto wholly synthetic platforms. Recent advances point to a burgeoning area of study which may soon bear fruit in some of the holy grails of polymer synthesis, namely sequence (and stereo) control, single chain manipulation, and controlled polymer folding. This Perspective seeks to summarize recent developments in the area of nucleobase containing polymers (including nucleobase mimics), with particular emphasis on controlled polymerization, self-assembly, and templating polymerization.
|Item Type:||Journal Article|
|Divisions:||Faculty of Science > Chemistry|
|Journal or Publication Title:||Macromolecules|
|Publisher:||American Chemical Society|
|Page Range:||pp. 7665-7675|
|Access rights to Published version:||Restricted or Subscription Access|
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