Degradable graft copolymers by ring-opening and reverse addition–fragmentation chain transfer polymerization
Williams, Rebecca J., O'Reilly, Rachel K. and Dove, Andrew P.. (2012) Degradable graft copolymers by ring-opening and reverse addition–fragmentation chain transfer polymerization. Polymer Chemistry, Vol.3 (No.8). pp. 2156-2164. ISSN 1759-9954Full text not available from this repository.
Official URL: http://dx.doi.org/10.1039/C2PY20213A
The synthesis and controlled ring-opening polymerization (ROP) of a six membered cyclic carbonate monomer with pendant reversible addition–fragmentation chain transfer (RAFT) functionality is reported. The growth of fast propagating monomers (methyl acrylate, tetrahydropyran acrylate and N-isopropylacrylamide) from the obtained RAFT-functional poly(carbonate)s resulted in the formation of well-defined graft copolymers with a biodegradable backbone, when grafting was terminated at low monomer conversions (ca. 30%). Direct dissolution of the thermally responsive poly(carbonate)-graft-PNiPAm copolymer yielded spherical micelles as confirmed by DLS and TEM analysis.
|Item Type:||Journal Article|
|Divisions:||Faculty of Science > Chemistry|
|Journal or Publication Title:||Polymer Chemistry|
|Publisher:||Royal Society of Chemistry|
|Page Range:||pp. 2156-2164|
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