The Library
Asymmetric spermatocyte division as a mechanism for controlling sex ratios
Tools
Shakes, Diane C., Neva, Bryan J., Huynh, Henry, Chaudhuri, Jyotiska and Pires-da Silva, André Francisco (2011) Asymmetric spermatocyte division as a mechanism for controlling sex ratios. Nature Communications, Vol.2 (No.1). Article no. 157. doi:10.1038/ncomms1160 ISSN 2041-1723.
Research output not available from this repository.
Request-a-Copy directly from author or use local Library Get it For Me service.
Official URL: http://dx.doi.org/10.1038/ncomms1160
Abstract
Although Mendel's first law predicts that crosses between XY (or XO) males and XX females should yield equal numbers of males and females, individuals in a wide variety of metazoans transmit their sex chromosomes unequally and produce broods with highly skewed sex ratios. Here, we report two modifications to the cellular programme of spermatogenesis, which, in combination, help to explain why males of the free-living nematode species Rhabditis sp. SB347 sire <5% male progeny. First, the spermatogenesis programme involves a modified meiosis in which chromatids of the unpaired X chromosome separate prematurely, in meiosis I. Second, during anaphase II, cellular components essential for sperm motility are partitioned almost exclusively to the X-bearing sperm. Our studies reveal a novel cellular mechanism for the differential transmission of X-bearing sperm and suggest Rhabditis sp. SB347 as a useful model for studying sex chromosome drive and the evolution of new mating systems.
Item Type: | Journal Article | ||||
---|---|---|---|---|---|
Divisions: | Faculty of Science, Engineering and Medicine > Science > Life Sciences (2010- ) | ||||
Journal or Publication Title: | Nature Communications | ||||
Publisher: | Nature Publishing Group | ||||
ISSN: | 2041-1723 | ||||
Official Date: | 2011 | ||||
Dates: |
|
||||
Volume: | Vol.2 | ||||
Number: | No.1 | ||||
Page Range: | Article no. 157 | ||||
DOI: | 10.1038/ncomms1160 | ||||
Status: | Peer Reviewed | ||||
Publication Status: | Published | ||||
Access rights to Published version: | Restricted or Subscription Access |
Request changes or add full text files to a record
Repository staff actions (login required)
View Item |