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Identifying the intermolecular hydrogen-bonding supramolecular synthons in an indomethacin–nicotinamide cocrystal by solid-state NMR

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Maruyoshi, K., Iuga, Dinu, Antzutkin, Oleg N., Alhalaweh, Amjad, Velaga, Sitaram P. and Brown, Steven P.. (2012) Identifying the intermolecular hydrogen-bonding supramolecular synthons in an indomethacin–nicotinamide cocrystal by solid-state NMR. Chemical Communications, Vol. 48 (No. 88). p. 10844. ISSN 1359-7345

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Official URL: http://dx.doi.org/10.1039/C2CC36094B

Abstract

Two-dimensional 1H double-quantum and 14N–1H & 1H–13C heteronuclear magic-angle spinning (MAS) NMR spectra recorded at natural isotopic abundance identify specific intermolecular COOHNarom and CHaromOC hydrogen-bonding interactions in the solid-state structure of an indomethacin–nicotinamide cocrystal, thus additionally proving cocrystal formation.

Item Type: Journal Article
Divisions: Faculty of Science > Physics
Journal or Publication Title: Chemical Communications
Publisher: Royal Society of Chemistry
ISSN: 1359-7345
Date: 2012
Volume: Vol. 48
Number: No. 88
Page Range: p. 10844
Identification Number: 10.1039/C2CC36094B
Status: Peer Reviewed
Publication Status: Published
Access rights to Published version: Restricted or Subscription Access
URI: http://wrap.warwick.ac.uk/id/eprint/52103

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