Pattinson, K. T. S. and Imray, C. (Chris) (2005) Transcranial doppler and carotid artery disease strokes : more than just risk stratification. Stroke, Vol.36 (No.11). pp. 2340-2341. ISSN 0039-2499

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Abstract

Two important studies addressing the role of transcranial Doppler ultrasound (TCD) microemboli detection and stroke prevention have been published recently.1,2 Markus and MacKinnon1 studied 200 patients within 3 months of a focal neurological event. Their study demonstrated that the presence of microembolic signals detected during 1 hour of TCD monitoring was an independent predictor of future stroke and transient ischemic attack (TIA). Two major implications were proposed, first that TCD emboli detection could be useful for risk stratification in patients with carotid stenosis and, second, that the technique could be used to assess the efficacy of antithrombotic therapy. In the recently published Clopidogrel and Aspirin for Reduction of Emboli in Symptomatic Carotid Stenosis (CARESS) trial,2 dual antiplatelet therapy (aspirin plus clopidogrel) resulted in more effective control of microembolic signals than single antiplatelet therapy (aspirin alone). There was an associated reduction in the subsequent prevalence of TIAs and strokes.

Item Type:	Journal Item
Divisions:	Faculty of Medicine > Warwick Medical School > Metabolic and Vascular Health Faculty of Medicine > Warwick Medical School
Journal or Publication Title:	Stroke
Publisher:	Lippincott Williams & Wilkins
ISSN:	0039-2499
Date:	2005
Volume:	Vol.36
Number:	No.11
Page Range:	pp. 2340-2341
Status:	Peer Reviewed
Publication Status:	Published
Access rights to Published version:	Restricted or Subscription Access
Related URLs:	Publisher
URI:	http://wrap.warwick.ac.uk/id/eprint/52182

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