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Cytokinesis microtubule organisers at a glance
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Lee, K. Y., Davies, T. and Mishima, Masanori (2012) Cytokinesis microtubule organisers at a glance. Journal of Cell Science, Vol.125 (No.15). pp. 3495-3500. doi:10.1242/jcs.094672
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Official URL: http://dx.doi.org/10.1242/jcs.094672
Abstract
Cytokinesis is a fundamental step of cell proliferation, and its high-fidelity completion is crucial for stable maintenance of the genome (Ganem et al., 2007; Lacroix and Maddox, 2012). Anti-parallel microtubule bundle structures such as the central spindle and the midbody play various important roles throughout cytokinesis, from positioning of cleavage furrow to final separation of the two daughter cells (Barr and Gruneberg, 2007; Glotzer, 2009; Fededa and Gerlich, 2012). Although a large number of different factors that are important for abscission, including membrane trafficking machinery, localise to the midzone during cytokinesis (Caballe and Martin-Serrano, 2011; Guizetti and Gerlich, 2010; Neto and Gould, 2011), here we focus on the current understanding of protein–protein interactions between microtubule organisers and their regulators that form cytokinetic microtubule structures.
Item Type: | Journal Item | ||||
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Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Biomedical Sciences > Cell & Developmental Biology Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School |
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Journal or Publication Title: | Journal of Cell Science | ||||
Publisher: | The Company of Biologists Ltd. | ||||
ISSN: | 0021-9533 | ||||
Official Date: | 1 August 2012 | ||||
Dates: |
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Volume: | Vol.125 | ||||
Number: | No.15 | ||||
Page Range: | pp. 3495-3500 | ||||
DOI: | 10.1242/jcs.094672 | ||||
Status: | Peer Reviewed | ||||
Publication Status: | Published | ||||
Access rights to Published version: | Restricted or Subscription Access |
Data sourced from Thomson Reuters' Web of Knowledge
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