Bhattacharya, Sayantan, Choudhury, Amit Kumar, Ravi, Srinivasan, Morrissey, John R. and Mathew, G. (George). (2008) Six years survival on imatinib with no disease progression after diagnosis of metastatic duodenal gastrointestinal stromal tumour: a case report. Journal of Medical Case Reports, Vol.2 (No.110). ISSN 1752-1947

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Abstract

Introduction: A duodenal Gastrointestinal Stromal Tumour (GIST) is a rare finding and until recently advanced disease had a poor prognosis. A PubMed search revealed no reports of more than five years survival of inoperable GIST on chemotherapy with WHO performance status zero. Case Presentation: A 68 year old female was diagnosed with unresectable GIST in the duodenum with metastasis to liver, pancreas and omentum in November 2001. She was commenced on imatinib mesylate (Glivec) chemotherapy. This case report was prepared from the medical records and radiology reports. She had good tolerance with stable disease. After six years her CT scan showed no disease progression and her WHO performance status was zero. Conclusion: This report supports the view that imatinib is a safe and effective drug in controlling disease progression in advanced metastatic GIST and plays an important role in improving the patient's quality of life.

Item Type:	Journal Article
Subjects:	R Medicine > RC Internal medicine
Divisions:	Faculty of Medicine > Warwick Medical School > Clinical Sciences Research Institute (CSRI) Faculty of Medicine > Warwick Medical School > Institute of Clinical Education (ICE) Faculty of Medicine > Warwick Medical School
Library of Congress Subject Headings (LCSH):	Duodenum -- Diseases, Gastrointestinal stronal tumours, Chemotherapy
Journal or Publication Title:	Journal of Medical Case Reports
Publisher:	BioMed Central Ltd.
ISSN:	1752-1947
Date:	18 April 2008
Volume:	Vol.2
Number:	No.110
Identification Number:	10.1186/1752-1947-2-110
Status:	Peer Reviewed
Publication Status:	Published
Access rights to Published version:	Open Access
Related URLs:	Organisation
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URI:	http://wrap.warwick.ac.uk/id/eprint/529

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