Leigh, Simon J., Gilbert, Hamish T. J., Barker, Ian A., Becker, Jan M., Richardson, Stephen M., Hoyland, Judith A., Covington, James A. and Dove, Andrew P. (2013) Fabrication of 3-dimensional cellular constructs via microstereolithography using a simple, three-component, poly(ethylene glycol) acrylate-based system. Biomacromolecules, Vol.14 (No.1). pp. 186-192. doi:10.1021/bm3015736

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Abstract

A novel method for the production of inhibitor- and solvent-free resins suitable for three-dimensional (3D) microstereolithography is reported. Using an exemplar poly(ethylene glycol)-based resin, the control of features in the X, Y, and Z planes is demonstrated such that complex structures can be manufactured. Human mesenchymal stem cells cultured on the manufactured scaffolds remained viable during the 7 day assessment period, with proliferation rates comparable to those observed on tissue culture polystyrene. These data suggest that this novel, yet simple, method is suitable for the production of 3D scaffolds for tissue engineering and regenerative medicine applications.

Item Type:	Journal Article
Divisions:	Faculty of Science, Engineering and Medicine > Science > Chemistry Faculty of Science, Engineering and Medicine > Engineering > Engineering
Journal or Publication Title:	Biomacromolecules
Publisher:	American Chemical Society
ISSN:	1525-7797
Official Date:	2013
Dates:	Date Event 2013 Published
Volume:	Vol.14
Number:	No.1
Page Range:	pp. 186-192
DOI:	10.1021/bm3015736
Status:	Peer Reviewed
Publication Status:	Published

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