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The development and validation of a self-administered quality-ofl life outcome measure for young, active patients with symptomatic hip disease : the International Hip Outcome Tool (iHOT-33)
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(2012) The development and validation of a self-administered quality-ofl life outcome measure for young, active patients with symptomatic hip disease : the International Hip Outcome Tool (iHOT-33). Arthroscopy: The Journal of Arthroscopic & Related Surgery, Vol.28 (No.5). 595-610.e1. doi:10.1016/j.arthro.2012.03.013 ISSN 0749-8063.
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Official URL: http://dx.doi.org/10.1016/j.arthro.2012.03.013
Abstract
Purpose
The purpose of this study was to develop a self-administered evaluative tool to measure health-related quality of life in young, active patients with hip disorders.
Methods
This outcome measure was developed for active patients (aged 18 to 60 years, Tegner activity level ≥4) presenting with a variety of symptomatic hip conditions. This multicenter study recruited patients from international hip arthroscopy and arthroplasty surgeon practices. The outcome was created using a process of item generation (51 patients), item reduction (150 patients), and pretesting (31 patients). The questionnaire was tested for test-retest reliability (123 patients); face, content, and construct validity (51 patients); and responsiveness over a 6-month period in post-arthroscopy patients (27 patients).
Results
Initially, 146 items were identified. This number was reduced to 60 through item reduction, and the items were categorized into 4 domains: (1) symptoms and functional limitations; (2) sports and recreational physical activities; (3) job-related concerns; and (4) social, emotional, and lifestyle concerns. The items were then formatted using a visual analog scale. Test-retest reliability showed Pearson correlations greater than 0.80 for 33 of the 60 questions. The intraclass correlation statistic was 0.78, and the Cronbach α was .99. Face validity and content validity were ensured during development, and construct validity was shown with a correlation of 0.81 to the Non-Arthritic Hip Score. Responsiveness was shown with a paired t test (P ≤ .01), effect size of 2.0, standardized response mean of 1.7, responsiveness ratio of 6.7, and minimal clinically important difference of 6 points.
Conclusions
We have developed a new quality-of-life patient-reported outcome measure, the 33-item International Hip Outcome Tool (iHOT-33). This questionnaire uses a visual analog scale response format designed for computer self-administration by young, active patients with hip pathology. Its development has followed the most rigorous methodology involving a very large number of patients. The iHOT-33 has been shown to be reliable; shows face, content, and construct validity; and is highly responsive to clinical change. In our opinion the iHOT-33 can be used as a primary outcome measure for prospective patient evaluation and randomized clinical trials.
Item Type: | Journal Article | ||||
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Divisions: | Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School |
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Journal or Publication Title: | Arthroscopy: The Journal of Arthroscopic & Related Surgery | ||||
Publisher: | W.B. Saunders Co. | ||||
ISSN: | 0749-8063 | ||||
Official Date: | 2012 | ||||
Dates: |
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Volume: | Vol.28 | ||||
Number: | No.5 | ||||
Page Range: | 595-610.e1 | ||||
DOI: | 10.1016/j.arthro.2012.03.013 | ||||
Status: | Peer Reviewed | ||||
Publication Status: | Published | ||||
Access rights to Published version: | Restricted or Subscription Access |
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