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Don’t turn your back on the symptoms of psychosis : a proof-of-principle, quasi-experimental public health trial to reduce the duration of untreated psychosis in Birmingham, UK

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Connor, Charlotte, Birchwood, M. J., Palmer, Colin, Channa, Sunita, Freemantle, Nick, Lester, Helen, Patterson, Paul and Singh, Swaran P. (2013) Don’t turn your back on the symptoms of psychosis : a proof-of-principle, quasi-experimental public health trial to reduce the duration of untreated psychosis in Birmingham, UK. BMC Psychiatry, Volume 13 (Number 1). Article no. 67. doi:10.1186/1471-244X-13-67 ISSN 1471-244X.

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Official URL: http://dx.doi.org/10.1186/1471-244X-13-67

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Abstract

Background: Reducing the duration of untreated psychosis (DUP) is an aspiration of international guidelines for first episode psychosis; however, public health initiatives have met with mixed results. Systematic reviews suggest that greater focus on the sources of delay within care pathways, (which will vary between healthcare settings) is needed to achieve sustainable reductions in DUP (BJP 198: 256-263; 2011).
Methods/Design: A quasi-experimental trial, comparing a targeted intervention area with a ‘detection as usual’ area in the same city. A proof-of–principle trial, no a priori assumptions are made regarding effect size; key outcome will be an estimate of the potential effect size for a definitive trial. DUP and number of new cases will be collected over an 18-month period in target and control areas and compared; historical data on DUP collected in both areas over the previous three years, will serve as a benchmark. The intervention will focus on reducing two significant DUP component delays within the overall care pathway: delays within the mental health service and help-seeking delay.
Discussion: This pragmatic trial will be the first to target known delays within the care pathway for those with a first episode of psychosis. If successful, this will provide a generalizable methodology that can be implemented in a variety of healthcare contexts with differing sources of delay.
Trial registration: http://www.controlled-trials.com/ISRCTN45058713
Keywords: Public mental health campaign, First-episode psychosis, Early detection, Duration of untreated psychosis, Youth mental health

Item Type: Journal Article
Subjects: R Medicine > R Medicine (General)
R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine
R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
Divisions: Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School > Health Sciences > Mental Health and Wellbeing
Faculty of Science, Engineering and Medicine > Medicine > Warwick Medical School
Library of Congress Subject Headings (LCSH): Psychoses, Psychoses in adolescence, Psychology, Pathological., Psychiatry -- Treatment , Psychoses -- Treatment, Psychoses in adolescence -- Treatment
Journal or Publication Title: BMC Psychiatry
Publisher: BioMed Central Ltd.
ISSN: 1471-244X
Official Date: 2013
Dates:
DateEvent
2013Published
Volume: Volume 13
Number: Number 1
Page Range: Article no. 67
DOI: 10.1186/1471-244X-13-67
Status: Peer Reviewed
Publication Status: Published
Access rights to Published version: Open Access (Creative Commons)
Date of first compliant deposit: 24 December 2015
Date of first compliant Open Access: 24 December 2015

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