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The cost-effectiveness of group cognitive behavioral therapy compared with routine primary care for women with postnatal depression in the UK

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Stevenson, M. (Matt), Scope, Alison and Sutcliffe, Paul A.. (2010) The cost-effectiveness of group cognitive behavioral therapy compared with routine primary care for women with postnatal depression in the UK. Value in Health, Vol.13 (No.5). pp. 580-584. ISSN 1098-3015

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Official URL: http://dx.doi.org/10.1111/j.1524-4733.2010.00720.x

Abstract

Objective: To assess the cost-effectiveness of group cognitive behavior therapy (gCBT) in comparison with routine primary care for women with postnatal depression in the UK. Methods: Our analysis was based on a systematic literature review of the relative clinical effectiveness of gCBT compared with routine primary care and further reviews, supplemented with expert opinion of the likely cost of providing gCBT and the duration of comparative advantage for gCBT. Raw data were used to estimate a statistical relationship between changes in the Edinburgh Postnatal Depression Score (EPDS) values and changes in short-form six dimensions' (SF-6D) values. A mathematical model was constructed, and probabilistic sensitivity analyses were undertaken to estimate the mean cost per quality-adjusted life-year (QALY) and to evaluate the expected value of perfect information (EVPI). Results: The mean cost per QALY from the stochastic analysis was estimated to be 36,062; pound however, there was considerable uncertainty around this value. The EVPI was estimated to be greater than 64 pound million; the key uncertainties were in the cost per woman of providing treatment and in the statistical relationship between changes in EPDS values and changes in SF-6D values. The expected value of perfect partial information for both of these parameters was in excess of 25 pound million. Conclusions: Given the current information, the use of gCBT does not appear to be cost-effective; however, this decision is uncertain. The value of information analyses conducted indicates that further research to provide robust information on key parameters is needed and appears justified in cost-effective terms.

Item Type: Journal Article
Subjects: R Medicine > R Medicine (General)
R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
R Medicine > RG Gynecology and obstetrics
Divisions: Faculty of Medicine > Warwick Medical School > Health Sciences
Faculty of Medicine > Warwick Medical School
Library of Congress Subject Headings (LCSH): Postpartum depression -- Treatment -- Great Britain, Cognitive therapy -- Cost effectiveness, Cognitive therapy -- Great Britain, Primary care (Medicine) -- Great Britain, Medical care, Cost of -- Great Britain
Journal or Publication Title: Value in Health
Publisher: Wiley-Blackwell Publishing, Inc
ISSN: 1098-3015
Date: July 2010
Volume: Vol.13
Number: No.5
Number of Pages: 5
Page Range: pp. 580-584
Identification Number: 10.1111/j.1524-4733.2010.00720.x
Status: Peer Reviewed
Publication Status: Published
Access rights to Published version: Restricted or Subscription Access
Funder: National Institute for Health Research (Great Britain) (NIHR)
URI: http://wrap.warwick.ac.uk/id/eprint/5397

Data sourced from Thomson Reuters' Web of Knowledge

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