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Severe lower respiratory tract infection in early infancy and pneumonia hospitalizations among children, Kenya
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Munywoki, Patrick Kiio, Ohuma, Eric O., Ngama, Mwanajuma, Bauni, Evasius, Scott, J. Anthony G. and Nokes, D. James (2013) Severe lower respiratory tract infection in early infancy and pneumonia hospitalizations among children, Kenya. Emerging Infectious Diseases , Volume 19 (Number 2). pp. 223-229. doi:10.3201/eid1902.120940
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Official URL: http://dx.doi.org/10.3201/eid1902.120940
Abstract
Severe lower respiratory tract infection (LRTI) in infants caused by respiratory syncytial virus (RSV) has been associated with later pneumonia hospitalization among children. To determine risk for pneumonia after RSV hospitalization in infancy, we conducted a retrospective cohort analysis of 2,813 infants admitted to a hospital in Kenya and identified readmissions for pneumonia among this group during early childhood (<60 months of age). Incidence of readmission for pneumonia was higher for children whose first admission as infants was for LRTI and who were <3 months of age than for children who were first admitted as infants for non-LRTI, irrespective of RSV status. Incidence of readmission for pneumonia with wheeze was higher for children whose first admission involved RSV compared with those who had non-RSV LRTI. Excess pneumonia risk persisted for 2 years after the initial hospitalization. Close postdischarge follow-up of infants with LRTI, with or without RSV, could help prevent severe pneumonia later in childhood.
| Item Type: | Journal Article | ||||
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| Subjects: | R Medicine > R Medicine (General) R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine |
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| Divisions: | Faculty of Science > Life Sciences (2010- ) | ||||
| Library of Congress Subject Headings (LCSH): | Pneumonia -- Kenya, Pneumonia in children -- Kenya, Pediatric respiratory diseases -- Kenya, Bronchitis in children -- Kenya, Public health surveillance -- Kenya -- Data processing, Children -- Diseases -- Kenya -- Data processing , Medical statistics | ||||
| Journal or Publication Title: | Emerging Infectious Diseases | ||||
| Publisher: | US Department of Health and Human Services | ||||
| ISSN: | 1080-6059 | ||||
| Official Date: | 2013 | ||||
| Dates: |
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| Date of first compliant deposit: | 24 December 2015 | ||||
| Volume: | Volume 19 | ||||
| Number: | Number 2 | ||||
| Page Range: | pp. 223-229 | ||||
| DOI: | 10.3201/eid1902.120940 | ||||
| Status: | Peer Reviewed | ||||
| Publication Status: | Published | ||||
| Access rights to Published version: | Open Access | ||||
| Funder: | Wellcome Trust (London, England) | ||||
| Grant number: | 061548, 076278, 084633, 081835, 092654 (WT) |
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