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Microfluidic systems for biosensing

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Liu, Kuo-Kang, Wu, Ren-Guei, Chuang, Yun-Ju, Khoo, Hwa Seng, Huang, Shih-Hao and Tseng, Fan-Gang (2010) Microfluidic systems for biosensing. Sensors, Vol.10 (No.7). pp. 6623-6661. ISSN 1424-8220

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Official URL: http://dx.doi.org/10.3390/s100706623

Abstract

In the past two decades, Micro Fluidic Systems (MFS) have emerged as a powerful tool for biosensing, particularly in enriching and purifying molecules and cells in biological samples. Compared with conventional sensing techniques, distinctive advantages of using MFS for biomedicine include ultra-high sensitivity, higher throughput, in-situ monitoring and lower cost. This review aims to summarize the recent advancements in two major types of micro fluidic systems, continuous and discrete MFS, as well as their biomedical applications. The state-of-the-art of active and passive mechanisms of fluid manipulation for mixing, separation, purification and concentration will also be elaborated. Future trends of using MFS in detection at molecular or cellular level, especially in stem cell therapy, tissue engineering and regenerative medicine, are also prospected.

Item Type:	Journal Item
Subjects:	Q Science > QH Natural history > QH301 Biology R Medicine > R Medicine (General) T Technology > TJ Mechanical engineering and machinery
Divisions:	Faculty of Science > Engineering
Library of Congress Subject Headings (LCSH):	Microfluidic devices, Biosensors
Journal or Publication Title:	Sensors
Publisher:	MDPI AG
ISSN:	1424-8220
Date:	July 2010
Volume:	Vol.10
Number:	No.7
Number of Pages:	39
Page Range:	pp. 6623-6661
Identification Number:	10.3390/s100706623
Status:	Peer Reviewed
Publication Status:	Published
Access rights to Published version:	Open Access
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URI:	http://wrap.warwick.ac.uk/id/eprint/5488