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Pollution prevention in the pharmaceutical industry
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Brems, Yannik, Lapkin, Alexei and Baeyens, Jan (2012) Pollution prevention in the pharmaceutical industry. International Journal of Sustainable Engineering . pp. 1-8. doi:10.1080/19397038.2012.730070 ISSN 1939-7038.
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Official URL: http://dx.doi.org/10.1080/19397038.2012.730070
Abstract
The pharmaceutical industry traditionally uses complex batch-type processes in the manufacture of medicines, although the production of specific medicines by continuous processes is currently envisaged. Due to the diversity of these processes, it is difficult to define a general set of waste prevention guidelines that would apply to all drug manufacturing. The most applicable methods of prevention can, however, be delineated for each of the five steps in the pharmaceutical manufacturing, i.e. (i) research and development, (ii) chemical synthesis, (iii) natural product extraction, (iv) fermentation and (v) product formulation. Waste streams generally arise from cleaning and sterilising equipment, chemical spills, rejected by-products and the processes themselves. Prevention mainly involves waste reduction by materials substitution, process modification/optimisation, waste stream segregation and solvent waste recycling. These measures are assessed and lead to guidelines for waste minimisation methods according to the waste streams under scrutiny.
Item Type: | Journal Article | ||||
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Divisions: | Faculty of Science, Engineering and Medicine > Engineering > Engineering | ||||
Journal or Publication Title: | International Journal of Sustainable Engineering | ||||
Publisher: | Taylor & Francis Ltd. | ||||
ISSN: | 1939-7038 | ||||
Official Date: | 2012 | ||||
Dates: |
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Page Range: | pp. 1-8 | ||||
DOI: | 10.1080/19397038.2012.730070 | ||||
Status: | Peer Reviewed | ||||
Publication Status: | Published | ||||
Description: | online first |
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