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Palladium-catalyzed multicomponent synthesis of 2-aryl-2-imidazolines from aryl halides and diamines
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Geden, Joanna V., Pancholi, Alpa K. and Shipman, Michael (2013) Palladium-catalyzed multicomponent synthesis of 2-aryl-2-imidazolines from aryl halides and diamines. The Journal of Organic Chemistry, Volume 78 (Number 8). pp. 4158-4164. doi:10.1021/jo400252n ISSN 0022-3263.
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Official URL: http://dx.doi.org/10.1021/jo400252n
Abstract
An efficient palladium-catalyzed three-component reaction that combines aryl halides, isocyanides, and diamines provides access to 2-aryl-2-imidazolines in yields up to 96%. Through variation of the diamine component, the reaction can be extended to the synthesis of 2-aryl-1H-benzimidazoles and 2-aryl-1,4,5,6-tetrahydropyrimidines.
| Item Type: | Journal Article | ||||
|---|---|---|---|---|---|
| Divisions: | Faculty of Science, Engineering and Medicine > Science > Chemistry | ||||
| Journal or Publication Title: | The Journal of Organic Chemistry | ||||
| Publisher: | American Chemical Society | ||||
| ISSN: | 0022-3263 | ||||
| Official Date: | 2013 | ||||
| Dates: |
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| Volume: | Volume 78 | ||||
| Number: | Number 8 | ||||
| Page Range: | pp. 4158-4164 | ||||
| DOI: | 10.1021/jo400252n | ||||
| Status: | Peer Reviewed | ||||
| Publication Status: | Published | ||||
| Access rights to Published version: | Restricted or Subscription Access |
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