Howlin, Patricia, Elison, Sarah, Udwin, Orlee and Stinton, Chris. (2010) Cognitive, linguistic and adaptive functioning in Williams Syndrome: trajectories from early to middle adulthood. Journal of Applies Research in Intellectual Disabilities, Vol.23 (No.4). pp. 322-336. ISSN 1360-2322

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Abstract

Background Little is known about trajectories of cognitive functioning as individuals with Williams syndrome (WS) move though adulthood. Method The present study investigated cognitive, linguistic and adaptive functioning in adults with WS aged 19-55 years, using both cross-sectional and longitudinal approaches. Results Data from the cross-sectional study (n = 92; mean age = 32 years) indicated that IQ was comparable across age groups (Full-Scale IQ mean = 56-57) with Verbal IQ being slightly higher than Performance IQ. Daily Living Skills (as measured by the Vineland Adaptive Behavior Scales) were significantly higher in older individuals. Language abilities showed no consistent age-related differences. On formal tests of language, comprehension scores were higher than expressive language scores for almost all individuals, although this pattern was not replicated on the Vineland. In the longitudinal study, a follow-up of 47 individuals (mean age = 37 years) first assessed 12 years previously, similar trajectories were found. IQ remained very stable (FSIQ = 61-62 at both time points); there were significant improvements on the Social and Daily Living domains of the Vineland and significant decreases in Maladaptive scores. There were no improvements in language over time. Conclusions The data indicate that adults with WS (at least up to the age of 50 years) show no evidence of deterioration in cognitive skills. Adaptive abilities continue to develop although language shows relatively little improvement with time.

Item Type:	Journal Article
Subjects:	L Education > LB Theory and practice of education R Medicine > RM Therapeutics. Pharmacology
Divisions:	Faculty of Medicine > Warwick Medical School > Health Sciences Faculty of Medicine > Warwick Medical School
Journal or Publication Title:	Journal of Applies Research in Intellectual Disabilities
Publisher:	Wiley-Blackwell Publishing, Inc.
ISSN:	1360-2322
Date:	July 2010
Volume:	Vol.23
Number:	No.4
Number of Pages:	15
Page Range:	pp. 322-336
Identification Number:	10.1111/j.1468-3148.2009.00536.x
Status:	Peer Reviewed
Publication Status:	Published
Access rights to Published version:	Restricted or Subscription Access
Funder:	Baily Thomas Fund, WSF
URI:	http://wrap.warwick.ac.uk/id/eprint/5719

Data sourced from Thomson Reuters' Web of Knowledge

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