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Modelling charge transport in DNA using transfer matrices with diagonal terms

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Wells, Stephen A., Shih, Chi-Tin and Roemer, Rudolf A. (2010) Modelling charge transport in DNA using transfer matrices with diagonal terms. In: Kusmartsev, F. V. (Feo V.), (ed.) Condensed Matter Theories, Proceedings of the 32nd International Workshop. Singapore ; Hackensack, NJ: World Scientific Publishing Company, pp. 206-217. ISBN 9789814289146

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Abstract

There is increasing evidence that DNA can support a considerable degree of charge transport along the strand by hopping of holes from one base to another, and that this charge transport may be relevant to DNA regulation, damage detection and repair. A surprisingly useful amount of insight can be gained from the construction of simple tight-binding models of charge transport, which can be investigated using the transfer-matrix method. The data thus obtained indicate a correlation between DNA charge-transport properties and the locations of cancerous mutation. We review models for DNA charge transport and their extension to include more physically realistic diagonal-hopping terms.

Item Type: Book Item
Subjects: Q Science > QC Physics
Divisions: Faculty of Science > Physics
Faculty of Science > Centre for Scientific Computing
Library of Congress Subject Headings (LCSH): DNA, Charge transfer, Charge transfer -- Mathematical models
Publisher: World Scientific Publishing Company
Place of Publication: Singapore ; Hackensack, NJ
ISBN: 9789814289146
Book Title: Condensed Matter Theories, Proceedings of the 32nd International Workshop
Editor: Kusmartsev, F. V. (Feo V.)
Official Date: 2010
Dates:
DateEvent
2010Published
Volume: Vol.24
Number of Pages: 644
Page Range: pp. 206-217
Status: Peer Reviewed
Publication Status: Published
Version or Related Resource: Paper presented at: 32nd International Workshop on Condensed Matter Theories, Loughborough Univ, Loughborough UK, 12-19 Aug 2008. ; Wells, S. A., et al. (2009). Modelling charge transport in DNA using transfer matrices with diagonal terms. International Journal of Modern Physics B (IJMPB. 23(20-21), pp. 4138-4149.
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